Digitonin
Suppliers
Names
[ CAS No. ]:
11024-24-1
[ Name ]:
Digitonin
[Synonym ]:
MFCD00077729
DigitoninGr
(2α,3β,5α,15β,25R)-2,15-Dihydroxyspirostan-3-yl β-D-glucopyranosyl-(1->3)-β-D-galactopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->;3)]-β-D-glucopyranosyl-(1->4)-β-D-galactopyranoside
β-D-Galactopyranoside, (2α,3β,5α,15β,25R)-2,15-dihydroxyspirostan-3-yl O-β-D-glucopyranosyl-(1->3)-O-β-D-galactopyranosyl-(1->2)-O-[β-D-xylopyranosyl-(1->3)]-O-β-D-glucopy ranosyl-(1->4)-
galactopyranoside]
yl-(1.fwdarw.4)
β-D-galactopyranoside, (2α,3β,5α,15β,25R)-2,15-dihydroxyspirostan-3-yl O-β-D-glucopyranosyl-(1->3)-O-β-D-galactopyranosyl-(1->2)-O-[β-D-xylopyranosyl-(1->3)]-O-β-D-glucopyranosyl-(1->4)-
(2a,3b,5a,15b,25R)-2,15-Dihydroxyspirostan-3-yl O-b-D-glucopyranosyl-(1®3)-O-b-D-galactopyranosyl-(1®2)-O-(b-D-xylopyranosyl-(1®3))-O-b-D-glucopyranosyl-(1®4)-b-D-galactopyranoside
EINECS 234-255-6
DIGITIN
(2α,3β,5α,15β,25R)-2,15-Dihydroxyspirostan-3-yl β-D-glucopyranosyl-(1->3)-β-D-galactopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->;3)]-β-D-glucopyranosyl-(1->4)-β-D-galactopyran 
oside
Digitonin,Digitin
Digitonin
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Melting Point ]:
230-240ºC
[ Molecular Formula ]:
C56H92O29
[ Molecular Weight ]:
1229.312
[ Exact Mass ]:
1228.572388
[ PSA ]:
454.67000
[ LogP ]:
-0.62
[ Index of Refraction ]:
1.660
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- IH2050050
- CHEMICAL NAME :
- Digitonin
- CAS REGISTRY NUMBER :
- 11024-24-1
- BEILSTEIN REFERENCE NO. :
- 0078654
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C56-H92-O29
- MOLECULAR WEIGHT :
- 1229.48
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 90 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD10 - Lethal Dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 10 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TEST SYSTEM :
- Yeast - Saccharomyces cerevisiae
- DOSE/DURATION :
- 250 ppb
- REFERENCE :
- ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 407,186,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83375 No. of Facilities: 174 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1744 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83375 No. of Facilities: 104 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1495 (estimated) No. of Female Employees: 1234 (estimated)
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H311-H330
[ Precautionary Statements ]:
P260-P280-P284-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T
[ Risk Phrases ]:
R23/24/25
[ Safety Phrases ]:
S22-S28-S36/37-S45
[ RIDADR ]:
UN 3462
[ WGK Germany ]:
3
[ RTECS ]:
IH2050050
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1(a)
[ HS Code ]:
29389090
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