dihydroferulic acid

Names

[ Name ]:
dihydroferulic acid

[Synonym ]:
Benzenepropanoic acid, 4-hydroxy-3-methoxy-
EINECS 214-489-5
3-(4-Hydroxy-3-methoxyphenyl)propanoic acid
dihydroferulic acid
3-(4-Hydroxy-3-Methoxyphenyl)propionic Acid
MFCD00016558

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
376.5±27.0 °C at 760 mmHg

[ Melting Point ]:
87-93 °C

[ Molecular Formula ]:
C₁₀H₁₂O₄

[ Molecular Weight ]:
196.200

[ Flash Point ]:
151.1±17.2 °C

[ Exact Mass ]:
196.073563

[ PSA ]:
66.76000

[ LogP ]:
0.81

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.562

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

ferulic acid
Ethyl 3-(4-hydroxy-3-methoxyphenyl)propionate
3-[4-(Benzyloxy)-3-methoxyphenyl]propanoic acid
3-(4-acetoxy-3-methoxyphenyl)propanoic acid
3,4-Dihydroxyhydrocinnamic acid
Vanillin
Propanedioic acid,2-[(4-hydroxy-3-methoxyphenyl)methylene]-, 1,3-diethyl ester

DownStream

Methyl 3-(4-Hydroxy-3-methoxyphenyl)propionate
6-Hydroxy-5-Methoxy-1-Indanone
3-[4-(Benzyloxy)-3-methoxyphenyl]propanoic acid
8-Gingerol
10-Gingerol
4-Ethyl-2-methoxyphenol
1H-Inden-1-one,2,3-dihydro-5-methoxy-6-(phenylmethoxy)-
Ethyl 3-(4-hydroxy-3-methoxyphenyl)propionate
Matairesinol
3,4-Dihydroxyhydrocinnamic acid

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Development of a targeted method for twenty-three metabolites related to polyphenol gut microbial metabolism in biological samples, using SPE and UHPLC-ESI-MS/MS.

Talanta 128 , 221-30, (2014)

An increasing number of studies have concerned the profiling of polyphenol microbial metabolites, especially in urine or plasma, but only a few have regarded their accurate quantification. This study ...

Fate of microbial metabolites of dietary polyphenols in rats: is the brain their target destination?

ACS Chem. Neurosci. 6 , 1341-52, (2015)

Different polyphenol compounds are ingested when consuming a serving of fruits rich in polyphenols, spanning from one-phenol hydroxybenzoic acid to more complex polymeric compounds. Only a minor quant...

Chronic administration of a microencapsulated probiotic enhances the bioavailability of orange juice flavanones in humans.

Free Radic. Biol. Med. 84 , 206-14, (2015)

Orange juice (OJ) flavanones are bioactive polyphenols that are absorbed principally in the large intestine. Ingestion of probiotics has been associated with favorable changes in the colonic microflor...