Caryophyllene oxide

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Names

[ Name ]:
Caryophyllene oxide

[Synonym ]:
(1R,4R,6R,10S)-4,12,12-trimethyl-9-methylene-5-oxatricyclo[8.2.0.04,6]dodecane
(-)-b-Caryophyllene oxide
6,7-Epoxy-3(15)-caryophyllene
(−)-Caryophyllene oxide
4b,5a-Epoxycaryophyllene
(-)-b-Caryophyllene epoxide
(1R,4R,6R,10S)-4,12,12-Trimethyl-9-methylene-5-oxatricyclo[8.2.0.0]dodecane
(-)-Epoxydihydrocaryophyllene
(-)-caryophyllene oxide
5-Oxatricyclo(8.2.0.0(4,6))dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)-
b-Caryophyllene oxide
Caryophyllene 4b,5a-oxide
β-Caryophyllene oxide
EINECS 214-519-7
MFCD00134216
b-Caryophyllene epoxide
trans-caryophyllene oxide
5-Oxatricyclo[8.2.0.0]dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)-
caryophyllene oxide
(−)-Epoxycaryophyllene

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
279.7±19.0 °C at 760 mmHg

[ Melting Point ]:
62-63ºC(lit.)

[ Molecular Formula ]:
C₁₅H₂₄O

[ Molecular Weight ]:
220.350

[ Flash Point ]:
119.7±19.5 °C

[ Exact Mass ]:
220.182709

[ PSA ]:
12.53000

[ LogP ]:
4.57

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.507

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RP5530000

CHEMICAL NAME :: 5-Oxatricyclo(8.2.0.0(sup 4,6))dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)-

CAS REGISTRY NUMBER :: 1139-30-6

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C15-H24-O

MOLECULAR WEIGHT :: 220.39

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 21,661,1983 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 21,661,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 21,661,1983

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/38

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
RP5530000

[ HS Code ]:
29109000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

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