2',2'-Difluoro-2'-deoxyuridine

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Names

[ CAS No. ]:
114248-23-6

[ Name ]:
2',2'-Difluoro-2'-deoxyuridine

[Synonym ]:
2(1H)-Pyrimidinone, 1-(2-deoxy-2,2-difluoro-β-D-erythro-pentofuranosyl)-4-hydroxy-
1-(2-Deoxy-2,2-difluoro-β-D-erythro-pentofuranosyl)-4-hydroxy-2(1H)-pyrimidinone
Uridine, 2'-deoxy-2',2'-difluoro-
Gemcitabine impurity C
2',2'-Difluoro-2'-deoxyuridine
2′,2′-difluorodeoxyuridine
2'-Deoxy-2',2'-difluorouridine

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Melting Point ]:
147-149ºC

[ Molecular Formula ]:
C9H10F2N2O5

[ Molecular Weight ]:
264.183

[ Exact Mass ]:
264.055786

[ PSA ]:
104.55000

[ LogP ]:
-0.53

[ Index of Refraction ]:
1.587

[ Storage condition ]:
-20°C Freezer

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2′,2′-Difluoro-2′-deoxyuridine 3′,5′-Dibenzoate
  • 2'-deoxy-2',2'-difluorouridine-3',5'-dibenzoate
  • Gemcitabine HCl
  • gemcitabine

DownStream

Related Compounds

  • 1'-Epi 2',2'-Difluoro-2'-deoxyuridine
  • 2',2'-Difluoro-2'-deoxyuridine 3',5'-Dibenzoate
  • 1'-Epi 2',2'-Difluoro-2'-deoxyuridine 3',5'-Dibenzoate
  • 2',2'-difluoro-2'-deoxycytidine-3',5'-dibenzoate
  • 2',2'-Difluoro-2'-deoxycytidine-3',5'-dibenzoate
  • 4-N-octadecanoyl-2'-2'-difluoro-2'-deoxycytidine 5'-sodium phosphate