2',2'-Difluoro-2'-deoxyuridine
Modify Date: 2024-01-09 13:03:20
2',2'-Difluoro-2'-deoxyuridine structure
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Common Name | 2',2'-Difluoro-2'-deoxyuridine | ||
|---|---|---|---|---|
| CAS Number | 114248-23-6 | Molecular Weight | 264.183 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C9H10F2N2O5 | Melting Point | 147-149ºC | |
| MSDS | N/A | Flash Point | N/A | |
Use of 2',2'-Difluoro-2'-deoxyuridine2′,2′-Difluorodeoxyuridine (dFdU) is the main metabolite of Gemcitabine (HY-17026). 2′,2′-Difluorodeoxyuridine causes a concentration- and schedule- dependent radiosensitising effect in vitro[1]. |
| Name | 2',2'-Difluoro-2'-deoxyuridine |
|---|---|
| Synonym | More Synonyms |
| Description | 2′,2′-Difluorodeoxyuridine (dFdU) is the main metabolite of Gemcitabine (HY-17026). 2′,2′-Difluorodeoxyuridine causes a concentration- and schedule- dependent radiosensitising effect in vitro[1]. |
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| Related Catalog | |
| References |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Melting Point | 147-149ºC |
| Molecular Formula | C9H10F2N2O5 |
| Molecular Weight | 264.183 |
| Exact Mass | 264.055786 |
| PSA | 104.55000 |
| LogP | -0.53 |
| Index of Refraction | 1.587 |
| Storage condition | -20°C Freezer |
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~94%
2',2'-Difluoro-... CAS#:114248-23-6 |
| Literature: ALIOS BIOPHARMA, INC.; Beigelman, Leonid; Wang, Guangyi; Smith, David Bernard; Deval, Jerome; Prhavc, Marija Patent: US2013/165400 A1, 2013 ; Location in patent: Paragraph 0420; 0421 ; |
|
~91%
2',2'-Difluoro-... CAS#:114248-23-6 |
| Literature: Chou; Heath; Patterson; Poteet; Lakin; Hunt Synthesis, 1992 , # 6 p. 565 - 570 |
|
~%
2',2'-Difluoro-... CAS#:114248-23-6 |
| Literature: US2013/165400 A1, ; |
|
~%
2',2'-Difluoro-... CAS#:114248-23-6 |
| Literature: US2013/165400 A1, ; |
|
~%
2',2'-Difluoro-... CAS#:114248-23-6 |
| Literature: Journal of Organic Chemistry, , vol. 53, # 11 p. 2406 - 2409 |
| 2(1H)-Pyrimidinone, 1-(2-deoxy-2,2-difluoro-β-D-erythro-pentofuranosyl)-4-hydroxy- |
| 1-(2-Deoxy-2,2-difluoro-β-D-erythro-pentofuranosyl)-4-hydroxy-2(1H)-pyrimidinone |
| Uridine, 2'-deoxy-2',2'-difluoro- |
| Gemcitabine impurity C |
| 2',2'-Difluoro-2'-deoxyuridine |
| 2′,2′-difluorodeoxyuridine |
| 2'-Deoxy-2',2'-difluorouridine |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 2',2'-Difluoro-2'-deoxyuridine
- Price: ￥1796.0/250mg ￥4496.0/1g ￥1126.0/100mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Liu jia
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