Apaziquone
Suppliers
Names
[ CAS No. ]:
114560-48-4
[ Name ]:
Apaziquone
[Synonym ]:
Neoquin
NOR-701
1H-Indole-4,7-dione, 5-(1-aziridinyl)-3-(hydroxymethyl)-2-(3-hydroxy-1-propen-1-yl)-1-methyl-
EO-9
5-(1-Aziridinyl)-3-(hydroxymethyl)-2-(3-hydroxy-1-propen-1-yl)-1-methyl-1H-indole-4,7-dione
Apaziquonum
Apaziquone
EOquin
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
632.3±55.0 °C at 760 mmHg
[ Molecular Formula ]:
C15H16N2O4
[ Molecular Weight ]:
288.298
[ Flash Point ]:
336.2±31.5 °C
[ Exact Mass ]:
288.110992
[ PSA ]:
82.54000
[ LogP ]:
-1.36
[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C
[ Index of Refraction ]:
1.682
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NL7873970
- CHEMICAL NAME :
- 1H-Indole-4,7-dione, 5-(1-aziridinyl)-3-(hydroxymethyl)-2-(3-hydroxy-1-pro penyl)-1-methyl-, (E)-
- CAS REGISTRY NUMBER :
- 114560-48-4
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C15-H16-N2-O4
- MOLECULAR WEIGHT :
- 288.33
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >450 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EJCTEA European Journal of Cancer Part A. (Pergamon Press, c/o Elsevier Science, 660 White Plains Rd., Tarrytown, NY 10591) V.28A(4/5)- 1992- Volume(issue)/page/year: 29A,897,1993
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 13 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EJCTEA European Journal of Cancer Part A. (Pergamon Press, c/o Elsevier Science, 660 White Plains Rd., Tarrytown, NY 10591) V.28A(4/5)- 1992- Volume(issue)/page/year: 29A,897,1993