(2S,4R)-1-Boc-4-(tert-butyldimethylsilyloxy)-2-(hydroxyMethyl)pyrrolidine

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Names

[ CAS No. ]:
114676-67-4

[ Name ]:
(2S,4R)-1-Boc-4-(tert-butyldimethylsilyloxy)-2-(hydroxyMethyl)pyrrolidine

[Synonym ]:
Simvastatin Acid Ammonium Salt
simvastatin hydroxy acid,ammonium salt
Simvastatin acid ammonium

Chemical & Physical Properties

[ Molecular Formula ]:
C16H33NO4Si

[ Molecular Weight ]:
331.52300

[ Exact Mass ]:
331.21800

[ PSA ]:
59.00000

[ LogP ]:
3.31640

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2S,4R)-1-Boc-2-methylcarboxylate-4-tert-butyldimethylsilyloxy-pyrrolidine
  • Di-tert-butyl dicarbonate
  • tert-Butyldimethylsilyl chloride
  • Boc-Hyp-OMe
  • H-Hyp-OMe hydrochloride
  • (2S,4R)-METHYL 4-HYDROXYPYRROLIDINE-2-CARBOXYLATE
  • L-Hydroxyproline
  • Boc-Hyp-OH

DownStream

  • (2R,4R)-(+)-AZETIDINE-2,4-DICARBOXYLICACID

Related Compounds

  • 4-Chloro-5-(difluoromethyl)-3-hydroxypicolinic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide