(2S,4R)-1-Boc-4-(tert-butyldimethylsilyloxy)-2-(hydroxyMethyl)pyrrolidine

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Names

[ CAS No. ]:
114676-67-4

[ Name ]:
(2S,4R)-1-Boc-4-(tert-butyldimethylsilyloxy)-2-(hydroxyMethyl)pyrrolidine

[Synonym ]:
Simvastatin Acid Ammonium Salt
simvastatin hydroxy acid,ammonium salt
Simvastatin acid ammonium

Chemical & Physical Properties

[ Molecular Formula ]:
C16H33NO4Si

[ Molecular Weight ]:
331.52300

[ Exact Mass ]:
331.21800

[ PSA ]:
59.00000

[ LogP ]:
3.31640

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2S,4R)-1-Boc-2-methylcarboxylate-4-tert-butyldimethylsilyloxy-pyrrolidine
  • Di-tert-butyl dicarbonate
  • tert-Butyldimethylsilyl chloride
  • Boc-Hyp-OMe
  • H-Hyp-OMe hydrochloride
  • (2S,4R)-METHYL 4-HYDROXYPYRROLIDINE-2-CARBOXYLATE
  • L-Hydroxyproline
  • Boc-Hyp-OH

DownStream

  • (2R,4R)-(+)-AZETIDINE-2,4-DICARBOXYLICACID

Related Compounds

  • 2-(3-(Cyclohexylmethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • 2-(4-Aminopiperidin-1-yl)-3-fluorobenzonitrile hydrochloride
  • 3-(((3-Bromophenyl)sulfonyl)methyl)azetidine hydrochloride
  • (1r,4r)-Methyl 4-(((tetrahydro-2H-pyran-4-yl)amino)methyl)cyclohexanecarboxylate hydrochloride
  • 6-(Difluoromethoxy)-2-methoxy-1H-benzo[d]imidazole
  • N-(3-chloro-5-methoxybenzyl)cyclopropanamine hydrochloride
  • N-(3-chloro-5-methoxybenzyl)propan-2-amine
  • N-(3-chloro-5-methoxybenzyl)cyclobutanamine hydrochloride
  • N-Allyl-1,10-phenanthrolin-5-amine
  • 1-[5-(4-Methoxy-phenyl)-pyridin-2-yl]-ethylamine dihydrochloride
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