(2S,4R)-1-Boc-4-(tert-butyldimethylsilyloxy)-2-(hydroxyMethyl)pyrrolidine

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Names

[ CAS No. ]:
114676-67-4

[ Name ]:
(2S,4R)-1-Boc-4-(tert-butyldimethylsilyloxy)-2-(hydroxyMethyl)pyrrolidine

[Synonym ]:
Simvastatin Acid Ammonium Salt
simvastatin hydroxy acid,ammonium salt
Simvastatin acid ammonium

Chemical & Physical Properties

[ Molecular Formula ]:
C16H33NO4Si

[ Molecular Weight ]:
331.52300

[ Exact Mass ]:
331.21800

[ PSA ]:
59.00000

[ LogP ]:
3.31640

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2S,4R)-1-Boc-2-methylcarboxylate-4-tert-butyldimethylsilyloxy-pyrrolidine
  • Di-tert-butyl dicarbonate
  • tert-Butyldimethylsilyl chloride
  • Boc-Hyp-OMe
  • H-Hyp-OMe hydrochloride
  • (2S,4R)-METHYL 4-HYDROXYPYRROLIDINE-2-CARBOXYLATE
  • L-Hydroxyproline
  • Boc-Hyp-OH

DownStream

  • (2R,4R)-(+)-AZETIDINE-2,4-DICARBOXYLICACID

Related Compounds

  • (3-Methylpent-4-yn-1-yl)benzene
  • 4-(2,4-dioxo-4aH-quinazolin-3-yl)-N-[(4-fluorophenyl)methyl]butanamide
  • 4-[(2,4-dioxo-4aH-quinazolin-3-yl)methyl]-N-[(4-fluorophenyl)methyl]benzamide
  • N-(3-methylbutyl)-4-[(4-oxo-2-sulfanylidene-4aH-quinazolin-3-yl)methyl]benzamide
  • 6-morpholin-4-yl-3-(3-morpholin-4-ylpropyl)-2-sulfanylidene-6H-quinazolin-4-one
  • methyl 4-[7-bromo-2-(4,5-dimethyl-1,3-thiazol-2-yl)-3,9-dioxo-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrol-1-yl]benzoate
  • 2-(2-Bromophenyl)-5-methylimidazo[1,2-a]pyridine
  • 8-Dodecylsulfanyl-3-methyl-7-nonyl-4,5-dihydropurine-2,6-dione
  • 2,7-dimethyl-1-(3,4,5-trimethoxyphenyl)-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
  • 1-(3,4-dimethoxyphenyl)-2-(4-methylpyridin-2-yl)-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
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