Ethapon

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Names

[ CAS No. ]:
115-20-8

[ Name ]:
Ethapon

[Synonym ]:
Ethanol, 2,2,2-trichloro-
2,2,2-Trichloroethanol
Trichloroethyl alcohol
EINECS 204-071-0
MFCD00004677
Trichloroethanol
Ethapon

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
152.1±35.0 °C at 760 mmHg

[ Melting Point ]:
17.8 °C(lit.)

[ Molecular Formula ]:
C2H3Cl3O

[ Molecular Weight ]:
149.404

[ Flash Point ]:
45.8±25.9 °C

[ Exact Mass ]:
147.924942

[ PSA ]:
20.23000

[ LogP ]:
1.38

[ Vapour density ]:
5.16 (vs air)

[ Vapour Pressure ]:
1.3±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.499

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KM3850000
CHEMICAL NAME :
Ethanol, 2,2,2-trichloro-
CAS REGISTRY NUMBER :
115-20-8
BEILSTEIN REFERENCE NO. :
1697495
LAST UPDATED :
199710
DATA ITEMS CITED :
13
MOLECULAR FORMULA :
C2-H3-Cl3-O
MOLECULAR WEIGHT :
149.40
WISWESSER LINE NOTATION :
Q1XGGG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - respiratory depression Lungs, Thorax, or Respiration - other changes
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - respiratory depression Lungs, Thorax, or Respiration - other changes
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Behavioral - sleep
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Rectal
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - respiratory depression Lungs, Thorax, or Respiration - other changes
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4200 mg/kg/14D-I
TOXIC EFFECTS :
Blood - changes in other cell count (unspecified) Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - changes in calcium
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
14400 mg/kg/90D-I
TOXIC EFFECTS :
Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - changes in calcium Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
178 gm/L
REFERENCE :
TOERD9 Toxicological European Research. (S.P.E., 10, Ave. de Messine, 75008 Paris, France) V.1- 1978- Volume(issue)/page/year: 3,63,1981

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H318-H336

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R41

[ Safety Phrases ]:
S26-S39

[ RIDADR ]:
1760

[ WGK Germany ]:
1

[ RTECS ]:
KM3850000

[ Packaging Group ]:
III

[ HS Code ]:
29055910

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethyl trichloroacetate
  • Chloral hydrate
  • Chloral
  • trimethyl(2,2,2-trichloroethoxy)silane
  • tert-butyldimethyl(2,2,2-trichloroethoxy)silane
  • Trichloroacetyl chloride
  • Trichloroacetic acid
  • Formaldehyde
  • Chloroform
  • Cyclohexanol

DownStream

  • 2,2,2-trichloroethyl cyanate
  • 2,2,2-Trichloroethyl carbamate
  • 2-Phenylacetophenone
  • Diphenylmethane
  • Benzene,1,1',1'',1'''-(1,2-ethanediylidene)tetrakis-
  • 2,2,2-Trichloroethyl 3,5-Dihydroxybenzoate
  • 2,2,2-Trichloroethyl acrylate
  • tris(2,2,2-trichloroethyl) phosphate
  • diethyl 2,2,2-trichloroethyl phosphite
  • 2,4-Pentandione

Customs

[ HS Code ]: 2905590090

[ Summary ]:
2905590090 other halogenated, sulphonated, nitrated or nitrosated derivatives of acyclic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

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