Azacyclonol

Suppliers

Names

[ CAS No. ]:
115-46-8

[ Name ]:
Azacyclonol

[Synonym ]:
alpha,alpha-Diphenyl-4-piperidinomethanol
4-(α,α Diphenyl) piperidine methanol
Diphenyl(4-piperidinyl)methanol
a,a-Diphenyl-4-piperidinemethanol
γ-Pipradrol
MFCD00066980
Ataractan
4-Piperidinemethanol, α,α-diphenyl-
α,α-Diphenyl-4-piperidinemethanol
α-(4-Piperidyl)benzhydrol
azacyclonol
diphenyl(4-piperidyl)methanol
Psychosan
g-Pipradrol
diphenyl(piperidin-4-yl)methanol
α,α-Diphenyl-4-piperidinomethanol
Diphenyl (g-Pyridyl)carbinol
a-(4-Piperidyl)benzhydrol
4-(Diphenylhydroxymethyl)piperidine
EINECS 204-092-5
Calmeran

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
445.5±40.0 °C at 760 mmHg

[ Melting Point ]:
160-163 °C

[ Molecular Formula ]:
C18H21NO

[ Molecular Weight ]:
267.365

[ Flash Point ]:
142.0±18.0 °C

[ Exact Mass ]:
267.162323

[ PSA ]:
32.26000

[ LogP ]:
3.25

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.584

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TN0470000
CHEMICAL NAME :
4-Piperidinemethanol, alpha,alpha-diphenyl-
CAS REGISTRY NUMBER :
115-46-8
BEILSTEIN REFERENCE NO. :
0230221
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C18-H21-N-O
MOLECULAR WEIGHT :
267.40

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
650 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
220 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
177 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963

Safety Information

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RTECS ]:
TN0470000

[ HS Code ]:
29333999

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • α,α-diphenyl-1-(phenylmethyl)-4-piperidinemethanol
  • 4-(HYDROXY-DIPHENYL-METHYL)-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER
  • Isopropyl ether
  • ethyl 4-(hydroxydiphenylmethyl)piperidine-1-carboxylate
  • Bromobenzene
  • Ethyl 1-benzyl-4-piperidinecarboxylate
  • Ethyl Isonipecotate
  • Ethyl N-Cbz-piperidine-4-carboxylate
  • Diphenyl(4-pyridyl)methanol
  • (1-methylpiperidin-4-yl)-diphenylmethanol

DownStream

  • 4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butanal
  • 4-benzhydrylidenepiperidine
  • Terfenadine
  • Piperidine,4-(diphenylmethyl)-
  • Fexofenadine
  • Methyl 2-(4-(4-((4-((4-hydroxyphenyl)(phenyl)methyl)piperidin-1-yl)oxy)butyl)phenyl)-2-methylpropanoate
  • Methyl 2-(4-(1-hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)-2-methylpropanoate
  • ETHYL 4-[4-[4-(HYDROXYDIPHENYLMETHYL)-1-PIPERIDINYL]-1
  • 4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone
  • N-(1,3-benzodioxol-5-yl)-2-(5-methylfuran-2-yl)quinoline-4-carboxamide

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • Azacyclonol HCl