N6-Cbz-L-Lysine

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Names

[ CAS No. ]:
1155-64-2

[ Name ]:
N6-Cbz-L-Lysine

[Synonym ]:
N(ε)-Benzyloxycarbonyl-L-lysine
L-lysine, N-[hydroxy(phenylmethoxy)methylene]-, (E)-
6-N-Cbz-L-lysine
N6-[(phenylmethoxy)carbonyl]-L-lysine
L-Lysine, N-[(phenylmethoxy)carbonyl]-
N-[(Benzyloxy)carbonyl]-L-lysine
N6-(Benzyloxycarbonyl)-L-lysine
MFCD00002638
N6-Carbobenzyloxy-L-lysine
Nepsilon-Carbobenzyloxy-L-lysine
LYSINE(Z)-OH
N6-Cbz-L-Lysine
EINECS 214-585-7
LYS(Z)
Nε-Carbobenzoxy-L-lysine
Nε-Cbz-L-lysine
L-LYSINE(CBZ)
H-LYS(Z)-OH
H-LYS(CBZ)-OH
H-L-Lys(Z)-OH
(S)-N6-Benzyloxycarbonyllysine
L-Lys(Cbz)-OH
L-LYS(Z)

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
499.6±45.0 °C at 760 mmHg

[ Melting Point ]:
259ºC (dec.)

[ Molecular Formula ]:
C14H20N2O4

[ Molecular Weight ]:
280.320

[ Flash Point ]:
255.9±28.7 °C

[ Exact Mass ]:
280.142303

[ PSA ]:
101.65000

[ LogP ]:
1.36

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.550

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • L-Lysine
  • Benzyl chloroformate
  • L-(+)-Lysine monohydrochloride
  • Z(OMe)-Lys(Z)-OH
  • Benzyl 1H-benzotriazole-1-carboxylate
  • Z-Lys(Z)-OH
  • Carbonic acid,1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl phenylmethylester
  • N6-Cbz-L-Lysine benzyl ester hydrochloride
  • benzyl-8-quinolyl carbonate
  • carbonic acid monobenzyl ester

DownStream

  • 5-{[(Benzyloxy)carbonyl]amino}pentanoic acid
  • BENZYL2-OXOPIPERIDINE-1-CARBOXYLATE
  • nepsilon-carbobenzoxy-nalpha-tosyl-l-lysine
  • Biocytin
  • (s)-2-piperidinone-6-carboxylic acid
  • boc-lys(nicotinoyl)-oh
  • 2-benzamido-6-phenylmethoxycarbonylamino-hexanoic acid
  • L-Lysine
  • 3,4,5,6-tetrahydropyridine-2-carboxylic acid
  • Fmoc-Lys(Z)-OH

Articles

Transfection of cells mediated by biodegradable polymer materials with surface-bound polyethyleneimine.

Biotechnol. Prog. 16 , 254-257, (2000)

Poly(epsilon-CBZ-L-lysine) can be mixed with biodegradable polymers such as poly(D,L-lactic-co-glycolic acid) or poly(L-lactic acid) and formed into films, foams, or microspheres. Surface amino groups...

Production of microspheres with surface amino groups from blends of Poly(Lactide-co-glycolide) and Poly(epsilon-CBZ-L-lysine) and use for encapsulation.

Biotechnol. Prog. 15 , 763-767, (1999)

Microspheres were formed from blends of the biodegradable polymer poly(DL-lactic-co-glycolic acid) (PLGA) together with poly(epsilon-CBZ-L-lysine) (PCBZL) by a double-emulsification/solvent evaporatio...

Transformation of N epsilon-CBZ-L-lysine to CBZ-L-oxylysine using L-amino acid oxidase from Providencia alcalifaciens and L-2-hydroxy-isocaproate dehydrogenase from Lactobacillus confusus.

Appl. Microbiol. Biotechnol. 37(5) , 599-603, (1992)

Biotransformations were developed to oxidize N epsilon-carbobenzoxy(CBZ)-L-lysine and to reduce the product keto acid to L-CBZ-oxylysine. Lysyl oxidase (L-lysine: O2 oxidoreductase, EC 1.4.3.14) from ...


More Articles

Related Compounds

  • N6-Cbz-L-Lysine benzyl ester hydrochloride
  • N6-cbz-L-lysine methyl ester hydrochloride
  • N'-Cbz-L-lysine tert-butyl ester hydrochloride
  • Nε-Cbz L-lysine methyl ester
  • Z-Lys(Z)-OH
  • Ne-Boc-L-lysine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 2-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]pentanoyl}-2-azabicyclo[2.1.1]hexane-1-carboxylic acid
  • 7-[(3-methoxyazetidin-3-yl)methyl]-1H-indazole
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4-Amino-1-(3,3-dimethylcyclopentyl)cyclohexane-1-carboxylic acid
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde