Edrophonium chloride
Suppliers
Names
[ CAS No. ]:
116-38-1
[ Name ]:
Edrophonium chloride
[Synonym ]:
edrophonium chloride
MFCD00055064
EINECS 204-138-4
Benzenaminium, N-ethyl-3-hydroxy-N,N-dimethyl-, chloride (1:1)
N-Ethyl-3-hydroxy-N,N-dimethylbenzenaminium chloride
Ethyl(m-hydroxyphenyl)dimethylammonium chloride
Tensilon
N-Ethyl-3-hydroxy-N,N-dimethylanilinium chloride
ethyl-(3-hydroxyphenyl)-dimethylazanium,chloride
Edrophonium (chloride)
Chemical & Physical Properties
[ Density]:
1.395 g/mL at 25 °C(lit.)
[ Boiling Point ]:
130 °C20 mm Hg(lit.)
[ Melting Point ]:
162-163°C
[ Molecular Formula ]:
C10H16ClNO
[ Molecular Weight ]:
201.693
[ Flash Point ]:
>230 °F
[ Exact Mass ]:
201.092041
[ PSA ]:
20.23000
[ Index of Refraction ]:
n20/D 1.486(lit.)
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
reacts
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BQ5870000
- CHEMICAL NAME :
- Ammonium, ethyl(m-hydroxyphenyl)dimethyl-, chloride
- CAS REGISTRY NUMBER :
- 116-38-1
- LAST UPDATED :
- 199504
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C10-H16-N-O.Cl
- MOLECULAR WEIGHT :
- 201.72
- WISWESSER LINE NOTATION :
- QR CK2&1&1 &G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 30 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 10,327,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 52 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - muscle weakness
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 123,121,1958
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 8500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 115,185,1955 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5548 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 8250 (estimated) No. of Female Employees: 7491 (estimated)
Safety Information
[ Hazard Codes ]:
Xi
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
BQ5870000
[ HS Code ]:
2923900090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2923900090
[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%