succinylsulfathiazole

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Names

[ CAS No. ]:
116-43-8

[ Name ]:
succinylsulfathiazole

[Synonym ]:
EINECS 204-141-0
Succinanilic acid, 4'-(2-thiazolylsulfamoyl)-
MFCD00022437
succinylsulfathiazole
4-(Succinylamino)-N-(2-thiazolyl)benzenesulfonamide Hydrate
Succinylsulfathiazole Hydrate
Butanoic acid, 4-oxo-4-[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]-
4-(Succinylamino)-N-(2-thiazolyl)benzenesulfonamide
N1-(2-THIAZOLYL)-N4-SUCCINOYLSULFANILAMIDE
N4-Succinyl-N-(2-thiazolyl)sulfanilamide Hydrate
N4-Succinyl-N-(2-thiazolyl)sulfanilamide
4-oxo-4-[4-(1,3-thiazol-2-ylsulfamoyl)anilino]butanoic acid
p-2-Thiazolylsulfamoylsuccinanilic acid
4-Oxo-4-{[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]amino}butanoic acid
4-oxo-4-{4-[(1,3-thiazol-2-ylamino)sulfonyl]anilino}butanoic acid

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Melting Point ]:
187 - 193ºC

[ Molecular Formula ]:
C₁₃H₁₃N₃O₅S₂

[ Molecular Weight ]:
355.389

[ Exact Mass ]:
355.029663

[ PSA ]:
162.08000

[ LogP ]:
0.68

[ Index of Refraction ]:
1.679

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WM4767000

CHEMICAL NAME :: Succinanilic acid, 4'-(2-thiazolylsulfamoyl)-

CAS REGISTRY NUMBER :: 116-43-8

BEILSTEIN REFERENCE NO. :: 0349989

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C13-H13-N3-O5-S2

MOLECULAR WEIGHT :: 355.41

WISWESSER LINE NOTATION :: T5N CSJ BMSWR DMV2VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 75,231,1942

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 7,151,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81640 No. of Facilities: 58 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 230 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H317

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R42/43

[ Safety Phrases ]:
S22-S36/37-S45

[ RIDADR ]:
3249

[ WGK Germany ]:
3

[ RTECS ]:
WM4767000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

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