succinylsulfathiazole
succinylsulfathiazole structure
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Common Name | succinylsulfathiazole | ||
|---|---|---|---|---|
| CAS Number | 116-43-8 | Molecular Weight | 355.389 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C13H13N3O5S2 | Melting Point | 187 - 193ºC | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of succinylsulfathiazoleSuccinylsulfathiazole is a sulfonamide, it is an ultra long acting drug. |
Summary: 4'-(2-Thiazolylsulfamoyl)succinanilic acid, also known as succinylsulfathiazole, CAS 116-43-8, with molecular formula C13H13N3O5S2 and molecular weight 355.389, is for research use only.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 4'-(2-Thiazolylsulfamoyl)succinanilic acid |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Succinylsulfathiazole is a sulfonamide, it is an ultra long acting drug. |
|---|---|
| Related Catalog |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Melting Point | 187 - 193ºC |
| Molecular Formula | C13H13N3O5S2 |
| Molecular Weight | 355.389 |
| Exact Mass | 355.029663 |
| PSA | 162.08000 |
| LogP | 0.68 |
| Index of Refraction | 1.679 |
| InChIKey | SKVLYVHULOWXTD-UHFFFAOYSA-N |
| SMILES | O=C(O)CCC(=O)Nc1ccc(S(=O)(=O)Nc2nccs2)cc1 |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H317 |
| Precautionary Statements | P280 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R42/43 |
| Safety Phrases | S22-S36/37-S45 |
| RIDADR | 3249 |
| WGK Germany | 3 |
| RTECS | WM4767000 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
| HS Code | 2935009090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~71%
succinylsulfath... CAS#:116-43-8 |
| Literature: Burdulene; Stumbryavichyute; Talaikite; Vladyko; Boreko; Korobchenko Pharmaceutical Chemistry Journal, 1997 , vol. 31, # 9 p. 471 - 473 |
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~%
succinylsulfath... CAS#:116-43-8 |
| Literature: Journal of the American Chemical Society, , vol. 64, p. 1572,1573, 1574 Journal of the Chemical Society, , p. 751 |
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~%
succinylsulfath... CAS#:116-43-8 |
| Literature: Journal of the American Chemical Society, , vol. 64, p. 1572,1573, 1574 |
|
~%
succinylsulfath... CAS#:116-43-8 |
| Literature: Journal of the American Chemical Society, , vol. 64, p. 1572,1573, 1574 |
|
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succinylsulfath... CAS#:116-43-8 |
| Literature: Journal of the American Chemical Society, , vol. 64, p. 1572,1573, 1574 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 6 | |
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| DownStream 0 | |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2935009090 |
|---|---|
| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Arsenic urinary speciation in Mthfr deficient mice injected with sodium arsenate.
Toxicol. Lett. 215(3) , 214-8, (2012) In most mammalian species, arsenic biotransformation occurs primarily by biomethylation and reduction reactions, with dimethylarsinic acid being the predominant metabolite excreted in the urine. Methy... |
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Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Eur. J. Med. Chem. 46 , 218-28, (2011) In order to minimize the high attrition rate that usually characterizes drug research and development projects, current medicinal chemists aim to characterize both pharmacological and ADME profiles at... |
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Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase.
J. Neurosci. 28 , 7219-7230, (2008) Folate deficiency and resultant increased homocysteine levels have been linked experimentally and epidemiologically with neurodegenerative conditions like stroke and dementia. Moreover, folate deficie... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273
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Name: Increase the activity of the Burkholderia fixLJ 2-component system
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Burkholderia multivorans
External Id: HMS1625
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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Name: qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity
Source: NCGC
External Id: HERG01
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Name: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen
Source: NCGC
Target: N/A
External Id: SMAD3201
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Name: uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay
Source: Burnham Center for Chemical Genomics
Target: cystic fibrosis transmembrane conductance regulator [Homo sapiens]
External Id: SBCCG-A764-CF-PAF-Primary-Assay
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ant...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_ANT_FLUO8_1536_1X%INH PRUN
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| EINECS 204-141-0 |
| MFCD00022437 |
| succinylsulfathiazole |
| 4-(Succinylamino)-N-(2-thiazolyl)benzenesulfonamide Hydrate |
| Succinylsulfathiazole Hydrate |
| 4-(Succinylamino)-N-(2-thiazolyl)benzenesulfonamide |
| N1-(2-THIAZOLYL)-N4-SUCCINOYLSULFANILAMIDE |
| N4-Succinyl-N-(2-thiazolyl)sulfanilamide Hydrate |
| N4-Succinyl-N-(2-thiazolyl)sulfanilamide |
| 4-oxo-4-[4-(1,3-thiazol-2-ylsulfamoyl)anilino]butanoic acid |
| p-2-Thiazolylsulfamoylsuccinanilic acid |
| 4-Oxo-4-{[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]amino}butanoic acid |
| 4-oxo-4-{4-[(1,3-thiazol-2-ylamino)sulfonyl]anilino}butanoic acid |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the safety information for 4'-(2-Thiazolylsulfamoyl)succinanilic acid? |
| A: Safety information for 4'-(2-Thiazolylsulfamoyl)succinanilic acid: S22-S36/37-S45. |
| Q: What is the melting point of 4'-(2-Thiazolylsulfamoyl)succinanilic acid? |
| A: Melting point of 4'-(2-Thiazolylsulfamoyl)succinanilic acid is 187 - 193ºC. |
| Q: What are the upstream materials of 4'-(2-Thiazolylsulfamoyl)succinanilic acid? |
| A: Related upstream materials(CAS) of 4'-(2-Thiazolylsulfamoyl)succinanilic acid: 108-30-5;72-14-0;36340-57-5;96-50-4;5694-39-3;110-15-6. |
| Q: What is the polar surface area (PSA) of 4'-(2-Thiazolylsulfamoyl)succinanilic acid? |
| A: Polar surface area (PSA) of 4'-(2-Thiazolylsulfamoyl)succinanilic acid is 162.08000. |
| Q: What is the molecular formula of 4'-(2-Thiazolylsulfamoyl)succinanilic acid? |
| A: Molecular formula of 4'-(2-Thiazolylsulfamoyl)succinanilic acid is C13H13N3O5S2. |
| Q: What is the CAS number of 4'-(2-Thiazolylsulfamoyl)succinanilic acid? |
| A: CAS number of 4'-(2-Thiazolylsulfamoyl)succinanilic acid is 116-43-8. |
| Q: What are the uses of 4'-(2-Thiazolylsulfamoyl)succinanilic acid? |
| A: Main uses of 4'-(2-Thiazolylsulfamoyl)succinanilic acid: Succinylsulfathiazole is a sulfonamide, it is an ultra long acting drug. |
| Q: What is the LogP of 4'-(2-Thiazolylsulfamoyl)succinanilic acid? |
| A: LogP of 4'-(2-Thiazolylsulfamoyl)succinanilic acid is 0.68. |
| Q: What is the InChIKey of 4'-(2-Thiazolylsulfamoyl)succinanilic acid? |
| A: InChIKey of 4'-(2-Thiazolylsulfamoyl)succinanilic acid is SKVLYVHULOWXTD-UHFFFAOYSA-N. |
| Q: What is the molecular weight of 4'-(2-Thiazolylsulfamoyl)succinanilic acid? |
| A: Molecular weight of 4'-(2-Thiazolylsulfamoyl)succinanilic acid is 355.389. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |