Phenamil methanesulfonate

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Names

[ CAS No. ]:
1161-94-0

[ Name ]:
Phenamil methanesulfonate

[Synonym ]:
2-Pyrazinecarboxamide, 3,5-diamino-N-[(1E)-amino(phenylamino)methylene]-6-chloro-, methanesulfonate (1:1)
Phenaethylphosphorodichloridat
MFCD00274070
2-Cl-IB-MECA
Phenamil methanesulfonate salt
3,5-Diamino-N-[(E)-amino(anilino)methylene]-6-chloro-2-pyrazinecarboxamide methanesulfonate (1:1)
Phosphorodichloridic acid,2-phenylethyl ester
3,5-Diamino-6-chloro-N-(N-phenylcarbamimidoyl)pyrazine-2-carboxamide methanesulfonate (1:1)

Chemical & Physical Properties

[ Boiling Point ]:
621.7ºC at 760 mmHg

[ Molecular Formula ]:
C13H16ClN7O4S

[ Molecular Weight ]:
401.829

[ Flash Point ]:
329.8ºC

[ Exact Mass ]:
401.067291

[ PSA ]:
205.55000

[ LogP ]:
3.38190

[ Vapour Pressure ]:
2.22E-15mmHg at 25°C

[ Storage condition ]:
-20°C

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2924299090

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

The lung amiloride-sensitive Na+ channel: biophysical properties, pharmacology, ontogenesis, and molecular cloning.

Proc. Natl. Acad. Sci. U. S. A. 91 , 247, (1994)

Water balance in the lung is controlled via active Na+ and Cl- transport. Electrophysiological measurements on lung epithelial cells demonstrated the presence of a Na+ channel that is inhibited by ami...

Phenamil: an irreversible inhibitor of sodium channels in the toad urinary bladder.

J. Membr. Biol. 87 , 45, (1985)

Several new amiloride analogues and two reported photoaffinity analogues were tested for irreversible inhibition of short-circuit current, Isc, in toad bladder. Bromoamiloride, a photoaffinity analogu...

Biochemical identification of two types of phenamil binding sites associated with amiloride-sensitive Na+ channels.

Biochemistry 28 , 3744, (1989)

The existence of distinct forms of the epithelium Na+ channel that differ in their sensitivity to amiloride has been repeatedly suggested by physiological data. The biochemical basis for these differe...


More Articles


Related Compounds

  • phenamil methanesulfonate salt
  • (3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-one,methanesulfonic acid
  • ergocristine methanesulfonate
  • Cesium methanesulfonate
  • Benzyl methanesulfonate
  • sodium,methanesulfonate,1-phenyl-2-propylhydrazine
  • {1-[(4-Methylthiophen-3-yl)methyl]cyclopropyl}methanamine
  • 1-methyl-3-(1,2,3-thiadiazol-4-yl)-1H-pyrazol-5-amine
  • 3-fluoro-3-[3-(trifluoromethyl)-1H-pyrazol-4-yl]propan-1-amine
  • 2-[5-propyl-1-(2,2,2-trifluoroethyl)-1H-1,2,3-triazol-4-yl]ethan-1-amine
  • 4-[4-(Propan-2-yl)cyclohexyl]butan-2-amine
  • 1-(1-ethyl-1H-pyrazol-3-yl)-2,2,2-trifluoroethan-1-amine
  • 1,1-Difluoro-2-(8-methoxy-2,3-dihydro-1,4-benzodioxin-6-yl)propan-2-amine
  • 3,3,3-Trifluoro-2-[2-(propan-2-yl)phenyl]propan-1-amine
  • 3-(1-Amino-2,2-difluorocyclopropyl)benzonitrile
  • 2-(1H-imidazol-5-yl)-1-propylpyrrolidin-3-amine
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