Phenamil methanesulfonate

Suppliers

Names

[ Name ]:
Phenamil methanesulfonate

[Synonym ]:
2-Pyrazinecarboxamide, 3,5-diamino-N-[(1E)-amino(phenylamino)methylene]-6-chloro-, methanesulfonate (1:1)
Phenaethylphosphorodichloridat
MFCD00274070
2-Cl-IB-MECA
Phenamil methanesulfonate salt
3,5-Diamino-N-[(E)-amino(anilino)methylene]-6-chloro-2-pyrazinecarboxamide methanesulfonate (1:1)
Phosphorodichloridic acid,2-phenylethyl ester
3,5-Diamino-6-chloro-N-(N-phenylcarbamimidoyl)pyrazine-2-carboxamide methanesulfonate (1:1)

Chemical & Physical Properties

[ Boiling Point ]:
621.7ºC at 760 mmHg

[ Molecular Formula ]:
C₁₃H₁₆ClN₇O₄S

[ Molecular Weight ]:
401.829

[ Flash Point ]:
329.8ºC

[ Exact Mass ]:
401.067291

[ PSA ]:
205.55000

[ LogP ]:
3.38190

[ Vapour Pressure ]:
2.22E-15mmHg at 25°C

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2924299090

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

The lung amiloride-sensitive Na+ channel: biophysical properties, pharmacology, ontogenesis, and molecular cloning.

Proc. Natl. Acad. Sci. U. S. A. 91 , 247, (1994)

Water balance in the lung is controlled via active Na+ and Cl- transport. Electrophysiological measurements on lung epithelial cells demonstrated the presence of a Na+ channel that is inhibited by ami...

Phenamil: an irreversible inhibitor of sodium channels in the toad urinary bladder.

J. Membr. Biol. 87 , 45, (1985)

Several new amiloride analogues and two reported photoaffinity analogues were tested for irreversible inhibition of short-circuit current, Isc, in toad bladder. Bromoamiloride, a photoaffinity analogu...

Biochemical identification of two types of phenamil binding sites associated with amiloride-sensitive Na+ channels.

Biochemistry 28 , 3744, (1989)

The existence of distinct forms of the epithelium Na+ channel that differ in their sensitivity to amiloride has been repeatedly suggested by physiological data. The biochemical basis for these differe...

phenamil methanesulfonate salt
(3S,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-one,methanesulfonic acid
ergocristine methanesulfonate
Cesium methanesulfonate
Benzyl methanesulfonate
sodium,methanesulfonate,1-phenyl-2-propylhydrazine
4,7-dimethoxy-2-{4-[6-(1-methyl-1H-pyrazol-4-yl)pyrazin-2-yl]piperazin-1-yl}-1,3-benzothiazole
4-(1-{5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl}azetidine-3-carbonyl)morpholine
4-(1-{6-Ethylthieno[2,3-d]pyrimidin-4-yl}azetidine-3-carbonyl)morpholine
2-({1-[(3,5-Difluorophenyl)methyl]piperidin-3-yl}methoxy)pyrazine
2-({1-[(2,5-Difluorophenyl)methyl]piperidin-3-yl}methoxy)pyrazine
N-{1-[(3-chlorophenyl)methyl]piperidin-3-yl}methanesulfonamide
N-{1-[(2,5-dimethylphenyl)methyl]piperidin-3-yl}methanesulfonamide
2-({1-[(3-Chlorophenyl)methyl]piperidin-3-yl}methoxy)pyrazine
2-({1-[(4-Chlorophenyl)methyl]piperidin-3-yl}methoxy)pyrazine
3-({1-[(2,4-Difluorophenyl)methyl]-5-oxopyrrolidin-3-yl}methyl)-1,3-diazaspiro[4.4]nonane-2,4-dione

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