SR 3576

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Names

[ CAS No. ]:
1164153-22-3

[ Name ]:
SR 3576

[Synonym ]:
SR-3576
Aminopyrazole inhibitor,3576

Chemical & Physical Properties

[ Molecular Formula ]:
C27H27N5O5

[ Molecular Weight ]:
501.53400

[ Exact Mass ]:
501.20100

[ PSA ]:
122.72000

[ LogP ]:
5.57340

[ Storage condition ]:
2-8°C

MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38.

J. Biol. Chem. 19th ed., 284 , 12853-12861, (2009)

c-Jun N-terminal kinase 3alpha1 (JNK3alpha1) is a mitogen-activated protein kinase family member expressed primarily in the brain that phosphorylates protein transcription factors, including c-Jun and...


More Articles


Related Compounds

  • SR 16832
  • SR 3677 dihydrochloride
  • SR 0987
  • SR-1277
  • SR 11302
  • SR-14150
  • 2-acetamido-4-(methylthio)-N-((6-(thiophen-3-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)butanamide
  • 2-(benzo[d][1,3]dioxol-5-yl)-N-((6-(thiophen-3-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)acetamide
  • 2-(6-oxopyridazin-1(6H)-yl)-N-((6-(thiophen-3-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)acetamide
  • 7-(1-amino-ethyl)-1-(3-methoxy-propyl)-4,4-dimethyl-6-p-tolyl-3,4-dihydro-1H-quinolin-2-one
  • 3-(1H-pyrazol-1-yl)-N-((6-(thiophen-3-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)benzamide
  • 2-hydroxy-N-((6-(thiophen-3-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)quinoline-4-carboxamide
  • N-((6-(thiophen-3-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)-6-(trifluoromethyl)nicotinamide
  • 5-chloro-6-hydroxy-N-((6-(thiophen-3-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)nicotinamide
  • 2-(2,4-difluorophenyl)-N-((6-(thiophen-3-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)acetamide
  • N-((6-(thiophen-3-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)tetrahydrofuran-3-carboxamide
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