SR 3576

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Names

[ CAS No. ]:
1164153-22-3

[ Name ]:
SR 3576

[Synonym ]:
SR-3576
Aminopyrazole inhibitor,3576

Chemical & Physical Properties

[ Molecular Formula ]:
C27H27N5O5

[ Molecular Weight ]:
501.53400

[ Exact Mass ]:
501.20100

[ PSA ]:
122.72000

[ LogP ]:
5.57340

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38.

J. Biol. Chem. 19th ed., 284 , 12853-12861, (2009)

c-Jun N-terminal kinase 3alpha1 (JNK3alpha1) is a mitogen-activated protein kinase family member expressed primarily in the brain that phosphorylates protein transcription factors, including c-Jun and...


More Articles

Related Compounds

  • SR 16832
  • SR 3677 dihydrochloride
  • SR 0987
  • SR-1277
  • SR 11302
  • SR-14150
  • 5-bromo-2-{[1-(3-methoxy-1-methyl-1H-pyrazole-4-carbonyl)piperidin-4-yl]methoxy}pyrimidine
  • 6-(3,5-dimethyl-1H-pyrazol-1-yl)-2-[1-(1,3-thiazol-2-yl)piperidin-4-yl]-2,3-dihydropyridazin-3-one
  • 2-(2-Chlorophenyl)-1-{3-[(pyridin-3-yloxy)methyl]azetidin-1-yl}ethan-1-one
  • 5-Fluoro-n-[(pyridin-4-yl)methyl]pyrimidin-4-amine
  • 5-chloro-N-{[1-(pyridine-3-sulfonyl)piperidin-4-yl]methyl}pyrimidin-2-amine
  • 2-({1-[1-(4-Fluorophenyl)cyclopropanecarbonyl]piperidin-4-yl}methoxy)pyrimidine
  • 2-({1-[1-(4-Fluorophenyl)cyclopropanecarbonyl]piperidin-3-yl}methoxy)pyrimidine
  • 2-(4-Fluorophenyl)-1-(3-{[(5-methylpyrimidin-2-yl)oxy]methyl}piperidin-1-yl)ethan-1-one
  • 1-Cyclopentyl-3-{3-[(morpholin-4-yl)methyl]-1,2-benzoxazol-5-yl}urea
  • 2-{[1-(4-Phenyloxane-4-carbonyl)piperidin-4-yl]methoxy}pyrimidine
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