SR 3576
Modify Date: 2024-01-23 16:26:42
SR 3576 structure
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Common Name | SR 3576 | ||
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| CAS Number | 1164153-22-3 | Molecular Weight | 501.53400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H27N5O5 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of SR 3576SR-3576 is a highly potent and selective JNK3 inhibitor with an IC50 of 7 nM[1]. |
| Name | 3-[4-[(3-methylphenyl)carbamoylamino]pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)benzamide |
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| Synonym | More Synonyms |
| Description | SR-3576 is a highly potent and selective JNK3 inhibitor with an IC50 of 7 nM[1]. |
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| Related Catalog | |
| Target |
JNK3:7 nM (IC50) |
| References |
| Molecular Formula | C27H27N5O5 |
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| Molecular Weight | 501.53400 |
| Exact Mass | 501.20100 |
| PSA | 122.72000 |
| LogP | 5.57340 |
| Storage condition | 2-8°C |
| RIDADR | NONH for all modes of transport |
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Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38.
J. Biol. Chem. 19th ed., 284 , 12853-12861, (2009) c-Jun N-terminal kinase 3alpha1 (JNK3alpha1) is a mitogen-activated protein kinase family member expressed primarily in the brain that phosphorylates protein transcription factors, including c-Jun and... |
| SR-3576 |
| Aminopyrazole inhibitor,3576 |