Dantron

Suppliers

Names

[ CAS No. ]:
117-10-2

[ Name ]:
Dantron

[Synonym ]:
EINECS 204-173-5
ALTAN
Chrysazin
Dionone
Modane
Laxapur
roydan
prugol
Duolax
Danivac
1,8-dihydroxy-anthraquinone
Istin
LTAN
Dorbane
Dantron
1,8-Dihydroxy-9,10-anthraquinone
1,8-Dihydroxyanthraquinone
9,10-Anthracenedione, 1,8-dihydroxy-
MFCD00001211
Danthron

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
452.7±35.0 °C at 760 mmHg

[ Melting Point ]:
191-193 °C(lit.)

[ Molecular Formula ]:
C₁₄H₈O₄

[ Molecular Weight ]:
240.211

[ Flash Point ]:
241.7±22.4 °C

[ Exact Mass ]:
240.042252

[ PSA ]:
74.60000

[ LogP ]:
4.57

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.733

[ Storage condition ]:
Refrigerator

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CB6650000

CHEMICAL NAME :: Anthraquinone, 1,8-dihydroxy-

CAS REGISTRY NUMBER :: 117-10-2

LAST UPDATED :: 199701

DATA ITEMS CITED :: 20

MOLECULAR FORMULA :: C14-H8-O4

MOLECULAR WEIGHT :: 240.22

WISWESSER LINE NOTATION :: L C666 BV IVJ DQ NQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1110 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Behavioral - muscle weakness Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >7 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 292 gm/kg/70W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Gastrointestinal - colon tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 129 gm/kg/77W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - colon tumors Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 130 gm/kg/77W-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - colon tumors

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 42 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 371,165,1996 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 50,265,1990 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 50,265,1990 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 50,265,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80355 No. of Facilities: 110 (estimated) No. of Industries: 2 No. of Occupations: 7 No. of Employees: 3120 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80355 No. of Facilities: 36 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 357 (estimated) No. of Female Employees: 187 (estimated)

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319-H351

[ Precautionary Statements ]:
P281-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R40

[ Safety Phrases ]:
S36/37

[ RIDADR ]:
2811

[ WGK Germany ]:
1

[ RTECS ]:
CB6650000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
29146990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4-hydroxy-10-imino-5-(methoxymethoxy)anthracen-9(10H)-one
3-(methoxymethoxy)-2-(4-oxo-4,5,6,7-tetrahydrobenzo[d]isoxazol-3-yl)benzaldehyde
5a-hydroxy-10-(methoxymethoxy)-3,4,5,5a-tetrahydro-6H-anthra[9,1-cd]isoxazol-6-one
3-(2-(1,3-dioxan-2-yl)-6-(methoxymethoxy)phenyl)-6,7-dihydrobenzo[d]isoxazol-4(5H)-one
9,10-Anthracenedione,1,8-bis(acetyloxy)-
1,4-dioxo-1,2,3,4-tetrahydro-5,9,10-trihydroxyanthracene(leuco 1,4,5-trihydroxy-9,10-anthraquinone)
3-hydroxy-2-(2-hydroxybenzoyl)benzoic acid
2-(2-hydroxybenzoyl)-3-nitrobenzoic acid
1,8-DINITROANTHRAQUINONE

DownStream

1,8,9-TRIHYDROXYANTHRACENE
9,10-Anthracenedione,1,8-bis(acetyloxy)-
1,4,5,8,9,10-Anthracenehexol
1,8-Dihydroxy-4,5-dinitroanthraquinone
1,8-dihydroxy-2,5-dinitroanthraquinone
1,4,5,8-Tetrahydroxy anthraquinone
3-Hydroxybenzoicacid
Salicylic acid
Dithranol
1,8,1',8'-tetrahydroxybisanthrone

Customs

[ HS Code ]: 2914690090

[ Summary ]:
2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Safety assessment of dietary bamboo charcoal powder: a 90-day subchronic oral toxicity and mutagenicity studies.

Food Chem. Toxicol. 75 , 50-7, (2015)

Vegetable carbon has been used as food additive in EU (E153) and China for many years; however, no experimental data have been available on its dietary safety. This study was designed to evaluate the ...

Determination of hydroxylated polycyclic aromatic hydrocarbons by HPLC-photoionization tandem mass spectrometry in wood smoke particles and soil samples.

Anal. Bioanal. Chem 407 , 4523-34, (2015)

A simple and fast method for analysis of hydroxylated polycyclic aromatic hydrocarbons using pressurized liquid extraction and high performance liquid chromatography utilizing photoionization tandem m...

1,4-dihydroxyanthraquinone electrochemical sensor based on molecularly imprinted polymer using multi-walled carbon nanotubes and multivariate optimization method.

Talanta 146 , 525-32, (2015)

The present work describes development of a simple and cost-effective electrochemical sensor for determination of 1,4-dihydroxyanthraquinone (1,4-DAQ) based on molecularly imprinted polypyrrole (PPY)....

Diacetyl-dantron
3-Bromochrysene
3-(3,4-Dimethoxyphenyl)-2,2-dimethylpropan-1-ol
1-Iodobut-2-yne
2-[4-(Bromomethyl)phenyl]ethan-1-amine
Methyl 2-[(phenoxyacetyl)amino]-1,3-benzothiazole-6-carboxylate
(2Z)-7-[(dibutylamino)methyl]-2-(2,4-dichlorobenzylidene)-6-hydroxy-1-benzofuran-3(2H)-one
C22H23Fino4
7-(4-fluorophenyl)-2-[4-(2-furoyl)piperazin-1-yl]-4-methyl-7,8-dihydroquinazolin-5(6H)-one
4-[1-(2-Phenylethenesulfonyl)piperidine-4-carbonyl]-1,2,3,4-tetrahydroquinoxalin-2-one
4-amino-N-(4-chlorophenyl)-2-(morpholin-4-yl)-7-oxo-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine-5-carboxamide

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.