5,8,11,14-Icosatetraynoic acid

Suppliers

Names

[ Name ]:
5,8,11,14-Icosatetraynoic acid

[Synonym ]:
Eicosa-5,8,11,14-tetrainsaeure
MFCD00036967
5,8,11,14-eicosatetrayonic acid
5,8,11,14-Icosatetraynoic acid
5,8,11,14-Eicosatetraynoic acid
ETYA
Icosa-5,8,11,14-tetraynoic acid
Octadehydroarachidonic acid
eicosatetraynoic acid

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
490.3±45.0 °C at 760 mmHg

[ Melting Point ]:
79-81ºC

[ Molecular Formula ]:
C₂₀H₂₄O₂

[ Molecular Weight ]:
296.403

[ Flash Point ]:
226.6±23.4 °C

[ Exact Mass ]:
296.177643

[ PSA ]:
37.30000

[ LogP ]:
5.19

[ Vapour Pressure ]:
0.0±2.7 mmHg at 25°C

[ Index of Refraction ]:
1.528

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2916190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Eicosa-5,8,11,14-tetrain-1-saeuremethylester
undeca-2,5-diyn-1-ol
1-bromo-2,5-undecadiyne
1-hydroxy-2,5,8-tetradecatriyne
1-bromo-2-octyne
5-Hexynoic acid
Hept-1-yne
5-cyano-1-pentyne
Methyl 5-hexynoate
1-bromotetradeca-2,5,8-triyne

DownStream

Arachidonic acid
Arachidonyl alcohol
Methyl (5Z,8Z,11Z,14Z)-5,8,11,14-icosatetraenoate
ARACHIDONIC ACID, [5,6,8,9,11,12,14,15-3H(N)]-

Customs

[ HS Code ]: 2916190090

[ Summary ]:
2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

Articles

Arachidonic acid induces brain endothelial cell apoptosis via p38-MAPK and intracellular calcium signaling.

Microvasc. Res. 98 , 145-58, (2015)

Arachidonic acid (AA), a bioactive fatty acid whose levels increase during neuroinflammation, contributes to cerebral vascular damage and dysfunction. However, the mode of injury and underlying signal...

High extracellular Ca2+ stimulates Ca2+-activated Cl- currents in frog parathyroid cells through the mediation of arachidonic acid cascade.

PLoS ONE 6(4) , e19158, (2011)

Elevation of extracellular Ca(2+) concentration induces intracellular Ca(2+) signaling in parathyroid cells. The response is due to stimulation of the phospholipase C/Ca(2+) pathways, but the direct m...

Reactive oxygen species mediate arachidonic acid-induced dilation in porcine coronary microvessels.

Am. J. Physiol. Heart Circ. Physiol. 285(6) , H2309-15, (2003)

Reactive oxygen species (ROS) have been proposed to mediate vasodilation in the microcirculation. We investigated the role of ROS in arachidonic acid (AA)-induced coronary microvascular dilation. Porc...

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