Bisindolylmaleimide IV

Suppliers

Names

[ CAS No. ]:
119139-23-0

[ Name ]:
Bisindolylmaleimide IV

[Synonym ]:
MFCD00236432
3,4-bis(1H-indol-3-yl)pyrrole-2,5-dione
2,3-bis-(1h-indol-3-yl)-maleimide
3,4-Bis(3-indolyl)maleimide
3,4-Di(1H-indol-3-yl)-1H-pyrrole-2,5-dione
1H-Pyrrole-2,5-dione, 3,4-di-1H-indol-3-yl-

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
690.1±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H13N3O2

[ Molecular Weight ]:
327.336

[ Flash Point ]:
371.2±31.5 °C

[ Exact Mass ]:
327.100769

[ PSA ]:
77.75000

[ LogP ]:
3.21

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.811

[ Storage condition ]:
-20℃

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Synthetic Route

Precursor & DownStream

Precursor

  • Indole-3-acetamide
  • Methyl indolyl-3-glyoxylate
  • 2,3-Dibromo-N-methylmaleimide
  • molecular iodine
  • 3,4-bis(1H-indol-3-yl)furan-2,5-dione
  • N-(2,4-dimethoxybenzyl)-2,3-bis-(3-indolyl)-maleimide
  • indole-3-glyoxylyl chloride
  • Indole
  • n-methylbis(indol-3-yl)maleimide
  • 1H-Indol-3-yl(oxo)acetic acid

DownStream

  • 3,4-bis(1-methyl-3-indolyl)-1-methyl-pyrrole-2,5-dione
  • n-methylbis(indol-3-yl)maleimide
  • 3-(1-methyl-3-indolyl)-4-(3-indolyl)-1-methyl-pyrrole-2,5-dione
  • Arcyriaflavin A

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Ca2+ influx through P2X1 receptors amplifies P2Y1 receptor-evoked Ca2+ signaling and ADP-evoked platelet aggregation.

Mol. Pharmacol. 86(3) , 243-51, (2014)

Many cells express both P2X cation channels and P2Y G-protein-coupled receptors that are costimulated by nucleotides released during physiologic or pathophysiologic responses. For example, during hemo...

High glucose-induced RhoA activation requires caveolae and PKCβ1-mediated ROS generation.

Am. J. Physiol. Renal Physiol. 302(1) , F159-72, (2012)

Glomerular matrix accumulation is a hallmark of diabetic nephropathy. We previously showed that RhoA activation by high glucose in mesangial cells (MC) leads to matrix upregulation (Peng F, Wu D, Gao ...

Entry of Newcastle Disease Virus into the host cell: role of acidic pH and endocytosis.

Biochim. Biophys. Acta 1838(1 Pt B) , 300-9, (2014)

Most paramyxoviruses enter the cell by direct fusion of the viral envelope with the plasma membrane. Our previous studies have shown the colocalization of Newcastle Disease Virus (NDV) with the early ...


More Articles


Related Compounds

  • Bisindolylmaleimide X HCl
  • Bisindolylmaleimide VII
  • Bisindolylmaleimide X(Ro 31-8425)
  • Bisindolylmaleimide II
  • 3-[8-[(dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methylindol-3-yl)pyrrole-2,5-dione
  • Bisindolylmaleimide III hydrochloride