1-((2R,5S)-5-((tert-butyldimethylsilyloxy)methyl)-2,5-dihydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

Names

[ CAS No. ]:
119794-49-9

[ Name ]:
1-((2R,5S)-5-((tert-butyldimethylsilyloxy)methyl)-2,5-dihydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

[Synonym ]:
5'-O-(tert-butyldimethylsilyl)-2',3'-didehydro-2',3'-dideoxyuridine
.5'-O-TBDMS-2',3'-didehydro-2',3'-dideoxyuridine

Chemical & Physical Properties

[ Molecular Formula ]:
C15H24N2O4Si

[ Molecular Weight ]:
324.44800

[ Exact Mass ]:
324.15100

[ PSA ]:
73.32000

[ LogP ]:
2.01200

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5'-O-(tert-butyldimethylsilyl)-2',3'-O-thionocarbonyluridine
  • 5'-O-(tert-butyldimethylsilyl)-2',3'-bis-O-[[(β-cyanoethyl)thio]thiocarbonyl]uridine

DownStream

  • 2',3'-Didehydro-2',3'-dideoxyuridine