CP-66248
Suppliers
Names
[ CAS No. ]:
120210-48-2
[ Name ]:
CP-66248
[Synonym ]:
TENIDAP
Tenidapum
(3Z)-5-chloro-3-[hydroxy(thiophen-2-yl)methylidene]-2-oxoindole-1-carboxamide
IL-6+Tenidap
(3Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-1H-indole-1-carboxamide CP 66248
Chemical & Physical Properties
[ Density]:
1.58g/cm3
[ Boiling Point ]:
523.9ºC at 760mmHg
[ Melting Point ]:
230° (dec)
[ Molecular Formula ]:
C14H9ClN2O3S
[ Molecular Weight ]:
320.75
[ Flash Point ]:
270.7ºC
[ Exact Mass ]:
320.00200
[ PSA ]:
111.87000
[ LogP ]:
4.01840
[ Appearance of Characters ]:
faint yellow to dark yellow
[ Vapour Pressure ]:
7.42E-13mmHg at 25°C
[ Index of Refraction ]:
1.756
[ Storage condition ]:
Store at +4°C
[ Water Solubility ]:
DMSO: soluble1mg/mL, clear (warmed)
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
22
[ RIDADR ]:
NONH for all modes of transport
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Clin. Exp. Immunol. 111(3) , 588-96, (1998)
Since IL-8 and MCP-1 are chemoattractant proteins that participate in the recruitment of inflammatory cells into the arthritic joint, we examined the effects of tenidap, a new anti-inflammatory drug o...
Pflugers Arch. 442(5) , 709-17, (2001)
In the present experiments we expressed the rat kidney Na+-HCO3- cotransporter (rkNBC) in Xenopus laevis oocytes to reinvestigate the flux coupling ratio under improved measuring conditions. Essential...
Ann. Rheum. Dis. 55(2) , 79-82, (1996)