VU 0364849

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Names

[ CAS No. ]:
1206711-14-9

[ Name ]:
VU 0364849

[Synonym ]:
DMH2
4-(6-{4-[2-(4-Morpholinyl)ethoxy]phenyl}pyrazolo[1,5-a]pyrimidin-3-yl)quinoline
VU0364849
4-[6-[4-[2-(4-Morpholinyl)ethoxy]phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline
Quinoline, 4-[6-[4-[2-(4-morpholinyl)ethoxy]phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Molecular Formula ]:
C27H25N5O2

[ Molecular Weight ]:
451.520

[ Exact Mass ]:
451.200836

[ LogP ]:
2.09

[ Index of Refraction ]:
1.689

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Small molecule antagonist of the bone morphogenetic protein type I receptors suppresses growth and expression of Id1 and Id3 in lung cancer cells expressing Oct4 or nestin.

Mol. Cancer 12(1) , 129, (2013)

Bone morphogenetic proteins (BMP) are embryonic morphogens that are aberrantly expressed in lung cancer. BMPs mediate cell fate decisions and self-renewal of stem cells, through transcription regulati...


More Articles

Related Compounds

  • VU 0360223
  • VU 590 dihydrochloride
  • VU 0038882
  • VU 0155041
  • VU 0365114
  • VU 1545
  • 6-Ethyl-5-fluoro-2-[5-(5-pyridin-3-yl-1,2-oxazole-3-carbonyl)-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-2-yl]-1,3-diazinan-4-one
  • 1-Benzyl-4-prop-2-ynylpiperazine-2,3-dione
  • 1-[(4-Methoxyphenyl)methyl]-4-[(4-oxopyrido[1,2-a]pyrimidin-2-yl)methyl]piperazine-2,3-dione
  • N-[1-(5-cyclopropylpyrazolidin-3-yl)piperidin-4-yl]-2-(1H-indol-3-ylsulfanyl)acetamide
  • 6-Phenyl-5-(4-pyridin-3-ylsulfonylpiperazin-1-yl)diazinan-3-one
  • 7-[(1-ethyl-5-methylpyrazol-4-yl)methyl-methylamino]-3-phenyl-4a,5,6,7,8,8a-hexahydro-1H-pyrimido[4,5-d]pyrimidine-2,4-dione
  • 3-[2-(4-fluorophenyl)-4-oxo-1,2,3,3a-tetrahydropyrazolo[1,5-a]pyrazin-5-yl]-N-(3-methylbutyl)propanamide
  • 5-fluoro-2-[4-(3-methoxy-1-methylpyrazole-4-carbonyl)piperazin-1-yl]-6-phenyl-5H-pyrimidin-4-one
  • 1-(2-Chlorophenyl)-4-prop-2-ynylpiperazine-2,3-dione
  • 1-(2-Ethoxyphenyl)-4-prop-2-ynylpiperazine-2,3-dione
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