VU 0364849

VU 0364849 Structure
VU 0364849 structure
Common Name VU 0364849
CAS Number 1206711-14-9 Molecular Weight 451.520
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C27H25N5O2 Melting Point N/A
MSDS USA Flash Point N/A

Small molecule antagonist of the bone morphogenetic protein type I receptors suppresses growth and expression of Id1 and Id3 in lung cancer cells expressing Oct4 or nestin.

Mol. Cancer 12(1) , 129, (2013)

Bone morphogenetic proteins (BMP) are embryonic morphogens that are aberrantly expressed in lung cancer. BMPs mediate cell fate decisions and self-renewal of stem cells, through transcription regulation of inhibitor of differentiation protein/DNA binding prot...