3-Deazaneplanocin A (hydrochloride)

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Names

[ CAS No. ]:
120964-45-6

[ Name ]:
3-Deazaneplanocin A (hydrochloride)

[Synonym ]:
3-Deazaneplanocin A (DZNep) hydrochloride
3-Deazaneplanocin A hydrochloride
3-deazaneplanocin A (DZNeP) HCl
CS-0870
3-Deazaneplanocin A (hydrochloride)

Chemical & Physical Properties

[ Melting Point ]:
168-169℃

[ Molecular Formula ]:
C12H15ClN4O3

[ Molecular Weight ]:
298.725

[ Exact Mass ]:
298.083282

[ PSA ]:
117.42000

[ LogP ]:
0.59190

[ Appearance of Characters ]:
white to beige

[ Storage condition ]:
?20°C

[ Water Solubility ]:
H2O: ≥5mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
NONH for all modes of transport

Articles

Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma.

Oncotarget 6 , 20555-69, (2015)

Aberrant activation of Janus kinase-3 (Jak3) and its key down-stream effectors, Signal Transducer and Activator of Transcription-3 (STAT3) and STAT5, is a key feature of malignant transformation in cu...


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Related Compounds

  • 3-deazaneplanocin
  • 3-[(A,A,A-TRIFLUORO-M-TOLYL)OXY]-PYRROLIDINE HYDROCHLORIDE
  • 3-[[2-(diaminomethylideneamino)-1,3-thiazol-4-yl]methylsulfanyl]propanimidamide,hydrochloride
  • 11H-pyrido[2,3-a]carbazole,hydrochloride
  • 11H-pyrido[2,3-a]carbazol-8-ol,hydrochloride
  • 8-methoxy-11H-pyrido[2,3-a]carbazole,hydrochloride
  • 2-(1,3-benzothiazol-2-yl)-1-(3-chlorophenyl)-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
  • 7-chloro-1-(2,3-dimethoxyphenyl)-6-methyl-2-pyridin-2-yl-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
  • 1-[4-[(2-chlorophenyl)methoxy]phenyl]-7-methyl-2-(5-methyl-1,2-oxazol-3-yl)-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
  • ethyl 2-[1-(3-fluorophenyl)-3,9-dioxo-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrol-2-yl]-1,3-benzothiazole-6-carboxylate
  • 7-chloro-2-(6-methoxy-1,3-benzothiazol-2-yl)-1-(2-methoxyphenyl)-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
  • 1-(3-ethoxyphenyl)-7-fluoro-2-(6-methylpyridin-2-yl)-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
  • methyl 4-[5,7-dichloro-2-(5-methyl-1,2-oxazol-3-yl)-3,9-dioxo-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrol-1-yl]benzoate
  • 3-[3-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-3-oxopropyl]-4aH-quinazoline-2,4-dione
  • 3-[1-[4-(3-chlorophenyl)piperazin-1-yl]-1-oxobutan-2-yl]-4a,5,6,7,8,8a-hexahydro-1H-quinazoline-2,4-dione
  • 2-(6-chloro-1,3-benzothiazol-2-yl)-1-(4-hydroxy-3-methoxyphenyl)-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
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