3-Deazaneplanocin A (hydrochloride)

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Names

[ CAS No. ]:
120964-45-6

[ Name ]:
3-Deazaneplanocin A (hydrochloride)

[Synonym ]:
3-Deazaneplanocin A (DZNep) hydrochloride
3-Deazaneplanocin A hydrochloride
3-deazaneplanocin A (DZNeP) HCl
CS-0870
3-Deazaneplanocin A (hydrochloride)

Chemical & Physical Properties

[ Melting Point ]:
168-169℃

[ Molecular Formula ]:
C12H15ClN4O3

[ Molecular Weight ]:
298.725

[ Exact Mass ]:
298.083282

[ PSA ]:
117.42000

[ LogP ]:
0.59190

[ Appearance of Characters ]:
white to beige

[ Storage condition ]:
?20°C

[ Water Solubility ]:
H2O: ≥5mg/mL

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
NONH for all modes of transport

Articles

Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma.

Oncotarget 6 , 20555-69, (2015)

Aberrant activation of Janus kinase-3 (Jak3) and its key down-stream effectors, Signal Transducer and Activator of Transcription-3 (STAT3) and STAT5, is a key feature of malignant transformation in cu...


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Related Compounds

  • 3-deazaneplanocin
  • 3-[(A,A,A-TRIFLUORO-M-TOLYL)OXY]-PYRROLIDINE HYDROCHLORIDE
  • 3-[[2-(diaminomethylideneamino)-1,3-thiazol-4-yl]methylsulfanyl]propanimidamide,hydrochloride
  • 11H-pyrido[2,3-a]carbazole,hydrochloride
  • 11H-pyrido[2,3-a]carbazol-8-ol,hydrochloride
  • 8-methoxy-11H-pyrido[2,3-a]carbazole,hydrochloride
  • Squamoxinone
  • 2-(Trifluoromethoxy)-8-naphthol
  • 7-(3-Aminophenyl)-5-ethoxycarbonyl-1-phenylbenzimidazole
  • 2-Bromo-1-(3-fluorophenyl)-2-(4-pyridyl)ethanone hydrocbromide
  • 5,6-Dimethyl-2-oxoindoline-1-carboxamide
  • 2-(2-Fluorobiphenyl-4-yl)-2-hydroxyacetic acid
  • (3I(2),4I+/-,16I+/-,21I(2),22I+/-)-28-(Acetyloxy)-16,22-dihydroxy-21-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-23-oxoolean-12-en-3-yl O-I(2)-D-galactopyranosyl-(1a2)-O-[O-I(2)-D-glucopyranosyl-(1a2)-I+/--L-arabinopyranosyl-(1a3)]-I(2)-D-glucopyranosiduronic acid
  • (2S,3S,4S,5R,6R)-6-[[(3S,4S,4aR,6aR,6bS,8R,8aR,9R,10R,12aS,14aR,14bR)-8a-(acetyloxymethyl)-4-formyl-8,9-dihydroxy-4,6a,6b,11,11,14b-hexamethyl-10-[(E)-2-methylbut-2-enoyl]oxy-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-4-[(2S,3R,4S,5S)-4,5-dihydroxy-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-3-hydroxy-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-2-carboxylic acid
  • Ethyl 5-[N-(4-methylbenzenesulfonyl)butanamido]-2-phenyl-1-benzofuran-3-carboxylate
  • (2S)-2-Amino-N,N-dimethyl-3-phenylpropanamide;hydrochloride
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