3-Deazaneplanocin A (hydrochloride)

3-Deazaneplanocin A (hydrochloride) Structure
3-Deazaneplanocin A (hydrochloride) structure
Common Name 3-Deazaneplanocin A (hydrochloride)
CAS Number 120964-45-6 Molecular Weight 298.725
Density N/A Boiling Point N/A
Molecular Formula C12H15ClN4O3 Melting Point 168-169℃
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma.

Oncotarget 6 , 20555-69, (2015)

Aberrant activation of Janus kinase-3 (Jak3) and its key down-stream effectors, Signal Transducer and Activator of Transcription-3 (STAT3) and STAT5, is a key feature of malignant transformation in cutaneous T-cell lymphoma (CTCL). However, it remains only pa...