N-Acetylserotonin

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Names

[ CAS No. ]:
1210-83-9

[ Name ]:
N-Acetylserotonin

[Synonym ]:
EINECS 214-916-5
N-acetyl-5-HT
N-Acetylserotonin
3-(2-Acetamidoethyl)-5-hydroxyindole
Serotonin, N-acetyl-
Normelatonin
N-Acetylserotonin,Normelatonin
Acetamide, N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-
N-Acetylserotonin Normelatonin
N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]acetamide
N-Acetyl-5-hydroxytryptamine
N-acetyl-serotonin
MFCD00005656
5-Hydroxymelatonin
5-Hydroxy-N-acetyltryptamine
N-ACETYL SEROTONIN

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
556.8±40.0 °C at 760 mmHg

[ Melting Point ]:
120-122 °C(lit.)

[ Molecular Formula ]:
C12H14N2O2

[ Molecular Weight ]:
218.252

[ Flash Point ]:
290.6±27.3 °C

[ Exact Mass ]:
218.105530

[ PSA ]:
65.12000

[ LogP ]:
-0.13

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.651

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
ethanol: 50 mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-ACETYL-5-BENZYLOXYTRYPTAMINE
  • Melatonine
  • [3-(2-acetamidoethyl)-1H-indol-5-yl] acetate
  • (5-Benzyloxyindol-3-yl)acetonitrile
  • Ethanoic anhydride
  • 1H-Indole-3-ethanamine,5-(phenylmethoxy)-
  • 5-Hydroxytryptamine
  • Acetyl chloride
  • Serotonin hydrochloride
  • 3-(2-AMINOETHYL)INDOL-5-OL CREATININE SULFATE

DownStream

  • 5-Methoxy-3-indoleaceate
  • Melatonine
  • N-[2-(1-hydroxy-5-methoxyindol-3-yl)ethyl]acetamide

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...

The antioxidant behaviour of melatonin and structural analogues during lipid peroxidation depends not only on their functional groups but also on the assay system.

Biochem. Biophys. Res. Commun. 423(4) , 873-7, (2012)

There is no general agreement yet on the antioxidant effect of pineal indoles against lipid peroxidation. Accordingly, the main goal of the present work was to study the antioxidant activity of melato...

Clock-Controlled Regulation of the Acute Effects of Norepinephrine on Chick Pineal Melatonin Rhythms.

J. Biol. Rhythms 30 , 519-32, (2015)

The chicken pineal gland synthesizes and releases melatonin rhythmically in light/dark (LD) cycles, with high melatonin levels during the dark phase, and in constant darkness (DD) for several cycles b...


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Related Compounds

  • N,N'-bis[2-(3,4-dimethoxyphenyl)ethyl]-N,N'-dimethylpropane-1,3-diamine
  • N-octanoyl benzotriazole
  • N-[4-[(6-chloro-[1,3]dioxolo[4,5-b]acridin-10-yl)amino]-3-methoxyphenyl]methanesulfonamide
  • N-(diaminomethylidene)pyrrolidine-1-carboximidamide,hydrochloride
  • N-phenyl-[1,3]dioxolo[4,5-b]acridin-10-amine
  • N-[bis(diethylamino)silyl]-N-ethylethanamine