Sarafotoxin C trifluoroacetate salt

[ Molecular Formula ]:
C₁₀₃H₁₄₇N₂₇O₃₇S₅

[ Molecular Weight ]:
2515.75000

[ Exact Mass ]:
2513.91000

[ PSA ]:
1172.52000

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Sarafotoxin S6c: an agonist which distinguishes between endothelin receptor subtypes.

Biochem. Biophys. Res. Commun. 175 , 556-561, (1991)

In contrast to endothelin-1 (ET-1) and several of its analogues, sarafotoxin S6c (S6c) was a much more potent inhibitor of [125I]-ET-1 binding in rat hippocampus and cerebellum (Ki approximately 20 pM...

Mechanisms of endothelin-induced venoconstriction in isolated guinea pig mesentery.

J. Pharmacol. Exp. Ther. 289 , 762-767, (1999)

In the present study, endothelin (ET) agonists and receptor selective antagonists were used to characterize ET receptors mediating constriction in guinea pig mesenteric veins (250-300 micrometers diam...

Influence of endothelins and sarafotoxin 6c and L-NAME on renal vasoconstriction in the anaesthetized rat.

Br. J. Pharmacol. 128 , 809-815, (1999)

1. An investigation was performed in pentobarbitone anaesthetized rats to compare the renal vasoconstrictor actions of endothelin-1 (ET-1), endothelin-3 (ET-3) and sarafotoxin 6c and their dependency ...

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