Sarafotoxin C trifluoroacetate salt
Sarafotoxin C trifluoroacetate salt structure
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Common Name | Sarafotoxin C trifluoroacetate salt | ||
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| CAS Number | 121695-87-2 | Molecular Weight | 2515.75000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C103H147N27O37S5 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Sarafotoxin S6c: an agonist which distinguishes between endothelin receptor subtypes.
Biochem. Biophys. Res. Commun. 175 , 556-561, (1991) In contrast to endothelin-1 (ET-1) and several of its analogues, sarafotoxin S6c (S6c) was a much more potent inhibitor of [125I]-ET-1 binding in rat hippocampus and cerebellum (Ki approximately 20 pM) than in rat atria and aorta (Ki approximately 4500 nM), s... |
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Mechanisms of endothelin-induced venoconstriction in isolated guinea pig mesentery.
J. Pharmacol. Exp. Ther. 289 , 762-767, (1999) In the present study, endothelin (ET) agonists and receptor selective antagonists were used to characterize ET receptors mediating constriction in guinea pig mesenteric veins (250-300 micrometers diameter) in vitro. The contribution of ET-evoked vasodilator r... |
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Influence of endothelins and sarafotoxin 6c and L-NAME on renal vasoconstriction in the anaesthetized rat.
Br. J. Pharmacol. 128 , 809-815, (1999) 1. An investigation was performed in pentobarbitone anaesthetized rats to compare the renal vasoconstrictor actions of endothelin-1 (ET-1), endothelin-3 (ET-3) and sarafotoxin 6c and their dependency on NO production. 2. Intra-renal arterial infusion of ET-1 ... |