Maleic hydrazide
Suppliers
Names
[ CAS No. ]:
123-33-1
[ Name ]:
Maleic hydrazide
[Synonym ]:
Vondalhyd
Yadi
MG-T
3(2H)-Pyridazinone, 6-hydroxy-
cis-Butenedioic acid hydrazide
MH-30
EINECS 204-619-9
3,6-Dihydroxypyridazine
3,6-dioxo-1,2,3,6-tetrahydropyridazine
1,2-Dihydro-3,6-pyridazinedione
T6VMMVJ
1,2-dihydro 3,6-pyridazinedione
pyridazine-3,6-diol
gotax
1,2,3,6-Tetrahydro-3,6-dioxopyridazine
MFCD00006665
1,2-dihydropyridazine-3,6-dione
Bos MH
KMH
6-hydroxy-2H-pyridazin-3-one
Fazor
Maleic hydrazine
T6NMVJ FQ
Yake
Hydrazide maleique
1,2-Dihydro-3,6-pyridazinedione,3,6-Dihydroxypyridazine,3,6-Pyridazinediol
Maleic Hydrazide
MH-40
3,6-Pyridazinedione, 1,2-dihydro-
mAh
3,6-Pyridazinediol
mH
Maleic acid cyclic hydrazide
T6NNJ CQ FQ
Maleic Acid Hydrazide
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
477.2±25.0 °C at 760 mmHg
[ Melting Point ]:
306-308 ºC
[ Molecular Formula ]:
C4H4N2O2
[ Molecular Weight ]:
112.087
[ Flash Point ]:
242.4±23.2 °C
[ Exact Mass ]:
112.027275
[ PSA ]:
65.72000
[ LogP ]:
-0.14
[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C
[ Index of Refraction ]:
1.640
[ Water Solubility ]:
6 g/L
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UR5950000
- CHEMICAL NAME :
- 3,6-Pyridazinedione, 1,2-dihydro-
- CAS REGISTRY NUMBER :
- 123-33-1
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 38
- MOLECULAR FORMULA :
- C4-H4-N2-O2
- MOLECULAR WEIGHT :
- 112.10
- WISWESSER LINE NOTATION :
- T6VMMVJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >20 gm/m3
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - quail
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - duck
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg/4W-I
- TOXIC EFFECTS :
- Endocrine - changes in thymus weight Immunological Including Allergic - increase in humoral immune response
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2600 mg/kg/65W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors Tumorigenic - tumors at site of application
- TYPE OF TEST :
- Specific locus test
- TYPE OF TEST :
- Cytogenetic analysis
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TYPE OF TEST :
- Cytogenetic analysis
- TYPE OF TEST :
- Cytogenetic analysis
- TYPE OF TEST :
- Cytogenetic analysis
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 100 ug/L
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 7,1,1985 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 4,173,1974 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 4,173,1974 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84780 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 124 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84780 No. of Facilities: 4 (estimated) No. of Industries: 1 No. of Occupations: 16 No. of Employees: 1440 (estimated)
Safety Information
[ Symbol ]:
GHS07, GHS08
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335-H341
[ Precautionary Statements ]:
P261-P281-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R36/37/38;R40
[ Safety Phrases ]:
S26-S36-S45-S36/37/39
[ RIDADR ]:
UN 3077 9/PG 3
[ WGK Germany ]:
2
[ RTECS ]:
UR5950000
[ HS Code ]:
2928000090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990011
[ Summary ]:
2933990011 o,o-diethyl o-quinoxalin-2-yl phosphorothioate。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%
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