Rivastigmine

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Names

[ CAS No. ]:
123441-03-2

[ Name ]:
Rivastigmine

[Synonym ]:
Carbamic acid, N-ethyl-N-methyl-, 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester
[3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate
MFCD03700731
(S)-N-ethyl-3-[(1-dimethylamino)ethyl]-N-methylphenylcarbamate
Rivastigmine
N-Ethyl-N-methylcarbamic acid 3-[(1S)-1-(dimethylamino)ethyl]phenyl-ester
(S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)carbamate
Ethylmethylcarbamic acid 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester
3-((1S)-1-(Dimethylamino)ethyl)phenyl ethylmethylcarbamate
carbamic acid, ethyl(methyl)-, 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester
3-[(1S)-1-(Dimethylamino)ethyl]phenyl ethyl(methyl)carbamate

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
316.2±34.0 °C at 760 mmHg

[ Molecular Formula ]:
C14H22N2O2

[ Molecular Weight ]:
250.34

[ Flash Point ]:
145.0±25.7 °C

[ PSA ]:
147.84000

[ LogP ]:
2.14

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.518

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethyl(methyl)carbamic chloride
  • 3-[(1S)-1-(Dimethylamino)ethyl]phenol
  • Carbamic acid, ethylmethyl-, 3-[(1R)-1-hydroxyethyl]phenyl ester
  • Dimethylamine
  • Formaldehyde
  • (S)-N-ethyl-3-[(1-dimethylamino)ethyl]-N-methylphenylcarbamate hydrochloride
  • Carbamic chloride, Methylpropyl-

DownStream

  • Ethylmethylamine
  • Carbon dioxide
  • 3-[(1S)-1-(Dimethylamino)ethyl]phenol

Related Compounds

  • RIVASTIGMINE
  • Rivastigmine
  • (R)-Rivastigmine
  • Diethyl RivastigMine
  • (rac)-Rivastigmine-d6
  • dimethyl-rivastigmine
  • N-(2,5-dimethylphenyl)-2-((3-(3,4-dimethylphenyl)-4-oxo-3,4-dihydrobenzofuro[3,2-d]pyrimidin-2-yl)thio)acetamide
  • 2-((3-(3,4-dimethylphenyl)-4-oxo-3,4-dihydrobenzofuro[3,2-d]pyrimidin-2-yl)thio)-N-(2-ethylphenyl)acetamide
  • 2-((4-oxo-3-(m-tolyl)-3,4-dihydrobenzofuro[3,2-d]pyrimidin-2-yl)thio)-N-phenylacetamide
  • 1-{8-benzoyl-2H,3H-[1,4]dioxino[2,3-g]quinolin-9-yl}-4-(3-chlorophenyl)piperazine
  • 1-{8-benzoyl-2H,3H-[1,4]dioxino[2,3-g]quinolin-9-yl}-4-(2-fluorophenyl)piperazine
  • 6-Methyl-4-(3-methylpiperidin-1-yl)-3-(phenylsulfonyl)quinoline
  • 1-[8-(benzenesulfonyl)-2H,3H-[1,4]dioxino[2,3-g]quinolin-9-yl]piperidine-4-carboxamide
  • 3-(4-Chlorobenzenesulfonyl)-6,7-dimethoxy-4-(piperidin-1-yl)quinoline
  • 3-(Benzenesulfonyl)-4-[4-(2-fluorophenyl)piperazin-1-yl]-6-methylquinoline
  • (4-Ethoxyphenyl)(6-fluoro-4-(phenylsulfonyl)quinolin-3-yl)methanone
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