1-Boc-4-piperidinemethanol

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Names

[ CAS No. ]:
123855-51-6

[ Name ]:
1-Boc-4-piperidinemethanol

[Synonym ]:
1-(tert-Butoxycarbonyl)-4-piperidinemethanol
N-BOC-4-Piperidinemethanol
MFCD02094488
N-tert-Butyloxycarbonyl-4-piperidinemethanol
1-Piperidinecarboxylic acid, 4-(hydroxymethyl)-, 1,1-dimethylethyl ester
1-Boc-4-(hydroxymethyl)piperidine
2-Methyl-2-propanyl 4-(hydroxymethyl)-1-piperidinecarboxylate
1-(tert-Butoxycarbonyl)-4-(hydroxymethyl)piperidine
tert-Butyl-4-(hydroxymethyl)piperidin-1-carboxylat
1-Boc-4-piperidinemethanol
tert-butyl 4-(Hydroxymethyl)piperidine-1-carboxylate
N-(tert-Butoxycarbonyl)-4-piperidinemethanol

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
308.0±15.0 °C at 760 mmHg

[ Melting Point ]:
78-82 °C(lit.)

[ Molecular Formula ]:
C11H21NO3

[ Molecular Weight ]:
215.29

[ Flash Point ]:
140.1±20.4 °C

[ Exact Mass ]:
215.152145

[ PSA ]:
49.77000

[ LogP ]:
0.88

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.479

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Ethyl N-Boc-piperidine-4-carboxylate
  • N-BOC-piperidine-4-carboxylic acid
  • 4-Piperidinemethanol
  • Di-tert-butyl dicarbonate
  • Ethyl chloroformate
  • N-Boc-Piperidine-4-carboxylic acid methyl ester
  • Potassium carbonate
  • Di-tert-butyl carbonate
  • Isonipecotic acid

DownStream

  • Methyl 5-hexynoate
  • tert-Butyl 4-(chloromethyl)piperidine-1-carboxylate
  • tert-butyl 4-(methylsulfonylmethyl)piperidine-1-carboxylate
  • tert-butyl 4-(2,2-dibromoethenyl)piperidine-1-carboxylate
  • TERT-BUTYL 4-((3-BROMOPHENOXY)METHYL)PIPERIDINE-1-CARBOXYLATE
  • 1-Boc-4-(3-hydroxypiperidin-1-ylmethyl)piperidine
  • 1-Boc-4-(3-hydroxyMethylpiperidin-1-ylmethyl)piperidine
  • 1-PIPERAZINECARBOXYLIC ACID,4-FORMYL-,1,1-DIMETHYLETHYL ESTER
  • 1-Boc-4-(2-thioxopiperidin-1-ylmethyl)piperidine
  • tert-Butyl (E)-4-(3-ethoxy-3-oxoprop-1-en-1-yl)piperidine-1-carboxylate

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synthesis and pharmacological evaluation of piperidinoalkanoyl-1,2,3,4-tetrahydroisoquinoline derivatives as novel specific bradycardic agents.

Bioorg. Med. Chem. Lett. 14 , 3049-3052, (2004)

A series of piperidinoalkanoyl-1,2,3,4-tetrahydroisoquinoline derivatives were synthesized, and their bradycardic activities were investigated in the isolated right atria of guinea pigs and in conscio...


More Articles

Related Compounds

  • 1-Boc-4-cyclohexyl-4-piperidineMethanol
  • 1-Boc-3-(1-phenylethylamino)-4-piperidinemethanol
  • 1-Boc-4-cbz-piperazine-2-carboxylic acid
  • 1-Boc-4-methoxypiperidine
  • 1-boc-4-[(2-cyano-ethyl)-pyridin-3-ylmethyl-amino]-piperidine
  • Tert-butyl 4-(ethylamino)piperidine-1-carboxylate
  • 2-[3-(anilinomethyl)-7-methoxy-2-oxoquinolin-1(2H)-yl]-N-(3-chlorophenyl)acetamide
  • N-(3,4-dimethoxyphenyl)-2-((4-(3,5-dimethylphenyl)-3-oxo-3,4-dihydropyrazin-2-yl)thio)acetamide
  • Methyl 3-((4-methylpiperidin-1-yl)sulfonyl)-4-phenylthiophene-2-carboxylate
  • methyl 2-((1,1-dioxido-3-oxo-2-(m-tolyl)-2H-benzo[e][1,2,4]thiadiazin-4(3H)-yl)methyl)-4-methoxybenzoate
  • 1-(3-chloro-4-fluorophenyl)-4-((4-ethylphenyl)sulfonyl)-1H-1,2,3-triazol-5-amine
  • N-(2-chlorobenzyl)-2-((4-(4-fluorophenyl)-3-oxo-3,4-dihydropyrazin-2-yl)thio)acetamide
  • N-(5-chloro-2-methoxyphenyl)-2-{[4-(4-fluorophenyl)-3-oxo-3,4-dihydropyrazin-2-yl]sulfanyl}acetamide
  • N-(2,5-dimethylphenyl)-2-((4-(4-fluorophenyl)-3-oxo-3,4-dihydropyrazin-2-yl)thio)acetamide
  • 3-Methoxy-6-prop-1-ynylpyridazine
  • N-(2,5-difluorophenyl)-2-((1,1-dioxido-4H-benzo[e][1,2,4]thiadiazin-3-yl)thio)acetamide
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