Tetra(hydroxymethyl)phosphonium chloride
Suppliers
Names
[ CAS No. ]:
124-64-1
[ Name ]:
Tetra(hydroxymethyl)phosphonium chloride
[Synonym ]:
Tetra(hydroxymethyl)phosphonium chloride
EINECS 204-707-7
Phosphonium, tetrakis(hydroxymethyl)-, chloride (1:1)
tetrakis(hydroxymethyl)phosphanium,chloride
MFCD00031687
Tetrakis(hydroxymethyl)phosphonium chloride
Chemical & Physical Properties
[ Density]:
1.341 g/mL at 25 °C
[ Boiling Point ]:
115°C/760mmHg
[ Melting Point ]:
154°C
[ Molecular Formula ]:
C4H12ClO4P
[ Molecular Weight ]:
190.562
[ Flash Point ]:
> 96ºC
[ Exact Mass ]:
190.016174
[ PSA ]:
94.51000
[ Index of Refraction ]:
n20/D 1.512
[ Water Solubility ]:
>=10 g/100 mL at 20 ºC
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TA2450000
- CHEMICAL NAME :
- Phosphonium, tetrakis(hydroxymethyl)-, chloride
- CAS REGISTRY NUMBER :
- 124-64-1
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 20
- MOLECULAR FORMULA :
- C4-H12-O4-P.Cl
- MOLECULAR WEIGHT :
- 190.58
- WISWESSER LINE NOTATION :
- Q1P1Q1Q1Q &G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 161 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 125 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 3800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7200 mg/kg/90D-I
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - sensory syndrome diagnostic of central lesion Behavioral - muscle weakness
MUTATION DATA
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 5000 ppm
- REFERENCE :
- JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 6,259,1980 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 48,95,1990 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 48,95,1990 TOXICOLOGY REVIEW CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 17,101,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0112 No. of Facilities: 25 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 100 (estimated)
Safety Information
[ Hazard Codes ]:
T:Toxic;N:Dangerousfortheenvironment;
[ Risk Phrases ]:
R21;R25;R38;R41;R42/43;R51/53
[ Safety Phrases ]:
S22-S26-S36/37/39-S45-S60-S61
[ RIDADR ]:
UN 2810 6.1/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
TA2450000
[ Packaging Group ]:
III
[ Hazard Class ]:
8
[ HS Code ]:
2931900090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2931900090
[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%