2-BUTYL-4-CHLORO-5-(HYDROXYMETHYL)-1-{[2'-[(TRIPHENYLMETHYL)TETRAZOLE-5YL]BIPHENYL-4-YL]METHYL}IMIDAZOLE

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Names

[ CAS No. ]:
124751-00-4

[ Name ]:
2-BUTYL-4-CHLORO-5-(HYDROXYMETHYL)-1-{[2'-[(TRIPHENYLMETHYL)TETRAZOLE-5YL]BIPHENYL-4-YL]METHYL}IMIDAZOLE

[Synonym ]:
N-Trityl Losartan
Trityllosartan

Chemical & Physical Properties

[ Density]:
1.225g/cm3

[ Boiling Point ]:
856.623ºC at 760 mmHg

[ Molecular Formula ]:
C41H37ClN6O

[ Molecular Weight ]:
665.22500

[ Flash Point ]:
471.868ºC

[ Exact Mass ]:
664.27200

[ PSA ]:
81.65000

[ LogP ]:
8.58040

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.656

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Butyl-4-chloro-5-formylimidazole
  • 5-(4'-(Bromomethyl)-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole
  • 5-(4'-Methyl-2-biphenylyl)-1-trityl-1H-tetrazole
  • (2-Butyl-5-chloro-1H-imidazol-4-yl)methanol
  • Triphenylmethyl Chloride
  • Losartan potassium
  • Losartan
  • 5-(2-Bromophenyl)-1-trityl-1H-tetrazole
  • 2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxaldehyde

DownStream

  • Methoxytriphenylmethane
  • Losartan
  • Losartan potassium
  • 2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxaldehyde