KT5823

Suppliers

Names

[ Name ]:
KT5823

[Synonym ]:
MFCD00132119
(9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-methoxy-2,9-dimethyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-l][1,6]benzodiazocine-10-carboxylic acid methyl ester

Chemical & Physical Properties

[ Density]:
1.52g/cm3

[ Boiling Point ]:
629.2ºC at 760mmHg

[ Molecular Formula ]:
C₂₉H₂₅N₃O₅

[ Molecular Weight ]:
495.52600

[ Flash Point ]:
334.3ºC

[ Exact Mass ]:
495.17900

[ PSA ]:
74.93000

[ LogP ]:
4.58930

[ Vapour Pressure ]:
9.67E-16mmHg at 25°C

[ Index of Refraction ]:
1.763

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Brain natriuretic peptide constitutively downregulates P2X3 receptors by controlling their phosphorylation state and membrane localization.

Mol. Pain 11 , 71, (2015)

ATP-gated P2X3 receptors are important transducers of nociceptive stimuli and are almost exclusively expressed by sensory ganglion neurons. In mouse trigeminal ganglion (TG), P2X3 receptor function is...

Interaction between bradykinin and natriuretic peptides via RGS protein activation in HEK-293 cells.

Am. J. Physiol. Cell Physiol. 303(12) , C1260-8, (2012)

In this study, the interaction of natriuretic peptides (NP) and bradykinin (BK) signaling pathways was identified by measuring membrane potential (V(m)) and intracellular Ca(2+) using the patch-clamp ...

Cytoprotective effect of 1-nitro-2-phenylethane in mice pancreatic acinar cells subjected to taurocholate: putative role of guanylyl cyclase-derived 8-nitro-cyclic-GMP.

Biochem. Pharmacol. 91(2) , 191-201, (2014)

The nitroderivative 1-nitro-2-phenylethane (NPE) was recently described as a compound possessing heme-dependent soluble guanylyl cyclase (sGC) stimulating properties in vascular smooth muscle cells. I...

2-(Methylsulfanyl)spiro[3.5]nonane-2-carboxylic acid
3-Methyl-1-(methylsulfanyl)cyclobutane-1-carboxylic acid
5-(Ethylsulfanyl)spiro[2.3]hexane-5-carboxylic acid
1-(Ethylthio)-3-isopropylcyclobutane-1-carboxylic acid
2,6-Dichloro-N,N-diethyl-4-(4-hydroxy-1-butyn-1-yl)benzenesulfonamide
1-(2-Amino-ethyl)-4-phenyl-piperidine-4-carboxylic acid benzyl-methyl-amide
1-(Methylthio)-3-phenylcyclobutane-1-carboxylic acid
3-Methyl-4-(piperidin-3-yloxy)pyridine
1-(2,4-Dicyclopropylphenyl)piperazine
Methyl 5-amino-2-((4-chlorobenzyl)oxy)benzoate

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