5-(and-6)-carboxy-2`,7`-dichlorofluorescein diacetate

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Names

[ CAS No. ]:
127770-45-0

[ Name ]:
5-(and-6)-carboxy-2`,7`-dichlorofluorescein diacetate

[Synonym ]:
5-(6)-CDCFDA [5(6)-Carboxy-2',7'-dichlorofluorescein Diacetate]
Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxylic acid, 3',6'-bis(acetyloxy)-2',7'-dichloro-3-oxo-
3',6'-Diacetoxy-2',7'-dichloro-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-5-carboxylic acid

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
743.3±60.0 °C at 760 mmHg

[ Melting Point ]:
210ºC (dec.)(lit.)

[ Molecular Formula ]:
C25H14Cl2O9

[ Molecular Weight ]:
529.279

[ Flash Point ]:
403.3±32.9 °C

[ Exact Mass ]:
528.001465

[ PSA ]:
125.43000

[ LogP ]:
3.66

[ Vapour Pressure ]:
0.0±2.6 mmHg at 25°C

[ Index of Refraction ]:
1.712

[ Storage condition ]:
-20°C

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

Articles

A high throughput in vitro mrp2 assay to predict in vivo biliary excretion.

Xenobiotica 42 , 157-163, (2012)

Prediction of biliary excretion is a challenge for drug discovery scientists due to the lack of in vitro assays. This study explores the possibility of establishing a simple assay to predict in vivo b...

Impact of probe compound in MRP2 vesicular transport assays.

Eur. J. Pharm. Sci. 46 , 100-105, (2012)

MRP2 is an efflux transporter that is expressed mainly in the canalicular membrane of hepatocytes, where it expels polar and ionic compounds into the bile. MRP2 is also present in the apical membrane ...

Molecular analysis of the yeast VPS3 gene and the role of its product in vacuolar protein sorting and vacuolar segregation during the cell cycle.

J. Cell Biol. 111 , 877, (1990)

vps3 mutants of the yeast Saccharomyces cerevisiae are impaired in the sorting of newly synthesized soluble vacuolar proteins and in the acidification of the vacuole (Rothman, J. H., and T. H. Stevens...


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