(2-Hydroxypropyl)-γ-cyclodextrin

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Names

[ CAS No. ]:
128446-34-4

[ Name ]:
(2-Hydroxypropyl)-γ-cyclodextrin

[Synonym ]:
2-fluoro-4-methyl-1-nitrobenzene
MFCD00007053
5,10,25-Tris(hydroxymethyl)-15,20,30,35,40-pentakis[(2-hydroxypropoxy)methyl]-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadecaoxanonacyclo[36.2.2.2.2.2.2.2.2 .2]hexapentacontane-41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56-hexadecol (non-preferred name)
EINECS 207-166-5
hydrxypropyl- gamma-cyclodextrin

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
97-98ºC3 mm Hg(lit.)

[ Melting Point ]:
52-55ºC(lit.)

[ Molecular Formula ]:
C7H6FNO2

[ Molecular Weight ]:
1587.521

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
1586.631958

[ PSA ]:
45.82000

[ LogP ]:
-8.72

[ Index of Refraction ]:
1.557

[ Storage condition ]:
2-8℃

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
26-36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

When administered to rats in a cold environment, 3,4-methylenedioxymethamphetamine reduces brown adipose tissue thermogenesis and increases tail blood flow: Effects of pretreatment with 5-HT1A and dopamine D2 antagonists

Neuroscience 154 , 1619-26, (2008)

When given in a warm environment MDMA (3,4-methylenedioxymethamphetamine, ecstasy) causes hyperthermia by increasing interscapular brown adipose tissue (iBAT) heat production and decreasing heat loss ...

Orexin/hypocretin signaling at the orexin 1 receptor regulates cue-elicited cocaine-seeking.

Eur. J. Neurosci. 30 , 493-503, (2009)

The orexin/hypocretin system has recently been implicated in reward-processing and addiction. We examined the involvement of the orexin system in cue-induced reinstatement of extinguished cocaine-seek...

The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73.

Cell Death Differ. 14 , 743-51, (2007)

Upon DNA damage signaling, p73, a member of the p53 tumor suppressor family, accumulates to support transcription of downstream apoptotic genes. p73 interacts with Yes-associated protein 1 (Yap1) thro...


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Related Compounds

  • (2-HYDROXYPROPYL)-ALPHA-CYCLODEXTRIN
  • 2-hydroxypropyl-α-cyclodextrin
  • (2-HYDROXYPROPYL)-BETA-CYCLODEXTRIN
  • 2-Hydroxypropyl 5-oxo-L-prolinate
  • 2-hydroxypropyl hydrogen maleate
  • 2-hydroxypropyl acetate
  • 5,9-Iminopyrimido[5,4-d]azocine-7,11(6H)-dicarboxylic acid, 5,8,9,10-tetrahydro-2-(methylthio)-, 7-(1,1-dimethylethyl) 11-(phenylmethyl) ester
  • 1,24-Bis(1,1-dimethylethyl) (7S,18S)-7,18-bis[[(1,1-dimethylethoxy)carbonyl]amino]-8,17-dioxo-12,13-dithia-2,9,16,23-tetraazatetracosanedioate
  • 1-Piperidinecarboxylic acid, 4-(4,5-dihydro-5-oxopyrazolo[1,5-a]pyrimidin-3-yl)-, 1,1-dimethylethyl ester
  • Amitraz hydrochloride (1:1)
  • Carbamic acid, N-[(1S)-1-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-3-methylbutyl]-, 1,1-dimethylethyl ester
  • 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-4-(hydroxymethyl)-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S,4S)-
  • 1,2-Dideoxy-3-C-(hydroxymethyl)-3-O-[2-(2-hydroxy-1-methylethoxy)-1-methylethyl]-5-O-(2-hydroxy-1-methylethyl)pentitol
  • Benzenepropanoic acid, I+/--[1-(cyclopropylamino)-2,2,2-trifluoroethylidene]-2-(ethoxycarbonyl)-, ethyl ester
  • 2,4-Dinitrophenyl (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
  • Carbamic acid, [(1R)-2-hydroxy-2-methyl-1-[[(tetrahydro-2H-pyran-2-yl)oxy]methyl]propyl]methyl-, 1,1-dimethylethyl ester
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