nevirapine

Suppliers

Names

[ Name ]:
nevirapine

[Synonym ]:
11-Cyclopropyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
nevirapine
11-Cyclopropyl-4-methyl-5H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6(11H)-one
MFCD00866928
Viramune
6H-Dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one, 11-cyclopropyl-5,11-dihydro-4-methyl-
11-cyclopropyl-4-methyl-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one
11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
415.4±45.0 °C at 760 mmHg

[ Melting Point ]:
247°C

[ Molecular Formula ]:
C₁₅H₁₄N₄O

[ Molecular Weight ]:
266.298

[ Flash Point ]:
205.0±28.7 °C

[ Exact Mass ]:
266.116760

[ PSA ]:
63.57000

[ LogP ]:
2.03

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.672

[ Storage condition ]:
-20°C Freezer

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S36/37

[ RIDADR ]:
UN 2206 6.1/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2934994000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

N-(2-CHLORO-4-METHYLPYRIDIN-3-YL)-2-(CYCLOPROPYLAMINO)NICOTINAMIDE
2-Chloro-N-(2-chloro-4-methylpyridin-3-yl)nicotinamide
Cyclopropanamine
7-chloro-5-cyclopropyl-9-methyl-5,10-dihydro-4,5,6,10-tetraaza-dibenzo[a,d]cyclohepten-11-one
2-Chloro-4-methyl-3-nitropyridine
Methyl tert-butyl ether
2-Chloronicotinyl chloride
2-Chlor-4-methylpyridin-3-amin
2-Chloronicotinic acid

DownStream

2-Nitro Nevirapine
2-Amino Nevirapine
11-Cyclopropyl-5,11-dihydro-4-(hydroxyMethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
2-Cyclopropylaminonicotinic acid
1'-cyclopropyl-4-methyl-1'H,2H-spiro[pyridine-3,2'-pyrido[2,3-d]pyrimidine]-2,4',6(1H,3'H)-trione

Customs

[ HS Code ]: 2934994000

[ Summary ]:
2934994000. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Livolin ameliorates elevations in alanine transaminase in HIV infected patients commencing highly active antiretroviral therapy.

Afr. J. Med. Med. Sci. 41(4) , 417-22, (2012)

HAART associated hepatoxicity is an important cause of poor adherence to therapy in HIV infected persons. An initial manifestation is elevation in the level ofAlanine Transaminase (ALT) in blood. We s...

Nucleoside reverse transcriptase inhibitor resistance mutations associated with first-line stavudine-containing antiretroviral therapy: programmatic implications for countries phasing out stavudine.

J. Infect. Dis. 207 Suppl 2 , S70-7, (2013)

The World Health Organization Antiretroviral Treatment Guidelines recommend phasing-out stavudine because of its risk of long-term toxicity. There are two mutational pathways of stavudine resistance w...

HIV testing in pregnancy.

Sex. Transm. Infect. 90(8) , 640, (2014)

NEVIRAPINE
Nevirapine-d4
Nevirapine-d3
Nevirapine Dimer
2-Amino Nevirapine
3-Bromo Nevirapine
1-(N-benzylamino)-1-cyclopropanemethanol
3-(3-Amino-5-oxo-4,5-dihydro-1H-pyrazol-4-yl)propanenitrile
2-chloro-6-fluoro-N-(5-((2-((2-fluorophenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)benzamide
N-(1-cyanocyclohexyl)-2-{[2-(4-fluorophenoxy)ethyl](methyl)amino}-N-methylacetamide
2-Benzyl-4-ethylsemicarbazide
1-Chloro-7-fluoro-4-methoxyisoquinoline
7-bromo-2-ethyl-1H-indole
2-(1,1,2,2,2-Pentafluoroethyl)oxirane
Butyl[(2,4,6-trimethylphenyl)methyl]amine
N-Butyl-1-(propan-2-yl)piperidin-4-amine

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