Bizelesin

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Names

[ CAS No. ]:
129655-21-6

[ Name ]:
Bizelesin

[Synonym ]:
Benzo(1,2-b:4,3-b')dipyrrol-4-ol,6,6'-(carbonylbis(imino-1H-indole-5,2-diylcarbonyl))bis(8-(chloromethyl)-3,6,7,8-tetrahydro-1-methyl-,(S-(R*,R*))
U-77,779
BIZELESIN
Bizelesin (USAN/INN)

Chemical & Physical Properties

[ Density]:
1.604g/cm3

[ Molecular Formula ]:
C43H36Cl2N8O5

[ Molecular Weight ]:
815.70300

[ Exact Mass ]:
814.21900

[ PSA ]:
185.37000

[ LogP ]:
9.52540

[ Index of Refraction ]:
1.856

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (S)-1-(chloromethyl)-1,6-dihydro-5-hydroxy-8-methylbenzo[1,2-b:4,3-b']dipyrrole hydrochloride
  • Ethyl 5-amino-1H-indole-2-carboxylate
  • (S)-1,6-dihydro-1-(hydroxymethyl)-8-methyl-5-(phenylmethoxy)-benzo[1,2-b:4,3-b']dipyrrole-3(2H)-carboxylic acid 1,1-dimethylethyl ester
  • (S)-1-(chloromethyl)-1,6-dihydro-8-methyl-5-(phenylmethoxy)-benzo[1,2-b:4,3-b']dipyrrole-3(2H)-carboxylic acid 1,1-dimethylethyl ester
  • (S)-6-tert-butyl 1-methyl 8-(acetoxymethyl)-4-(benzyloxy)-7,8-dihydropyrrolo[3,2-e]indole-1,6(3H)-dicarboxylate
  • 5,5'-(carbonyldiimino)bis-1H-indole-2-carboxylic acid diethyl ester
  • (1S)-3-[(tert-butyloxy)carbonyl]-1-(chloromethyl)-5-hydroxy-8-methyl-1,2-dihydro-3H-pyrrolo[3,2-e]indole

DownStream

Related Compounds

  • rac-1-[(2R,3S)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)oxolane-2-carbonyl]-3-methylpiperidine-3-carboxylic acid
  • rac-2-{[(2R,3S)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)oxolan-2-yl]formamido}-3,3,3-trifluoro-2-methylpropanoic acid
  • 1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoyl]-3-methylpiperidine-3-carboxylic acid
  • 1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanamido]cyclohexane-1-carboxylic acid
  • 3-{2-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanamido]ethoxy}propanoic acid
  • 1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoyl]pyrrolidine-3-carboxylic acid
  • 4-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N-(propan-2-yl)hexanamido]butanoic acid
  • 1-[(2S)-4-(benzyloxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-oxobutanoyl]-3-hydroxypiperidine-3-carboxylic acid
  • 4-[(2R,3S)-3-(benzyloxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-3-hydroxy-3-methylbutanoic acid
  • 2-[(2R,3S)-3-(benzyloxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-3-methoxy-2-methylpropanoic acid
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