Bizelesin

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Names

[ CAS No. ]:
129655-21-6

[ Name ]:
Bizelesin

[Synonym ]:
Benzo(1,2-b:4,3-b')dipyrrol-4-ol,6,6'-(carbonylbis(imino-1H-indole-5,2-diylcarbonyl))bis(8-(chloromethyl)-3,6,7,8-tetrahydro-1-methyl-,(S-(R*,R*))
U-77,779
BIZELESIN
Bizelesin (USAN/INN)

Chemical & Physical Properties

[ Density]:
1.604g/cm3

[ Molecular Formula ]:
C43H36Cl2N8O5

[ Molecular Weight ]:
815.70300

[ Exact Mass ]:
814.21900

[ PSA ]:
185.37000

[ LogP ]:
9.52540

[ Index of Refraction ]:
1.856

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (S)-1-(chloromethyl)-1,6-dihydro-5-hydroxy-8-methylbenzo[1,2-b:4,3-b']dipyrrole hydrochloride
  • Ethyl 5-amino-1H-indole-2-carboxylate
  • (S)-1,6-dihydro-1-(hydroxymethyl)-8-methyl-5-(phenylmethoxy)-benzo[1,2-b:4,3-b']dipyrrole-3(2H)-carboxylic acid 1,1-dimethylethyl ester
  • (S)-1-(chloromethyl)-1,6-dihydro-8-methyl-5-(phenylmethoxy)-benzo[1,2-b:4,3-b']dipyrrole-3(2H)-carboxylic acid 1,1-dimethylethyl ester
  • (S)-6-tert-butyl 1-methyl 8-(acetoxymethyl)-4-(benzyloxy)-7,8-dihydropyrrolo[3,2-e]indole-1,6(3H)-dicarboxylate
  • 5,5'-(carbonyldiimino)bis-1H-indole-2-carboxylic acid diethyl ester
  • (1S)-3-[(tert-butyloxy)carbonyl]-1-(chloromethyl)-5-hydroxy-8-methyl-1,2-dihydro-3H-pyrrolo[3,2-e]indole

DownStream

Related Compounds

  • N-methyl-N-(1-{[2-(trifluoromethyl)phenyl]methyl}piperidin-3-yl)cyclopropanesulfonamide
  • N-methyl-N-[1-(3-methylquinoxalin-2-yl)piperidin-3-yl]cyclopropanesulfonamide
  • 6-Chloro-2-[4-(cyclopropanesulfonyl)-1,4-diazepan-1-yl]quinoline
  • N-[1-(6-methoxyquinolin-2-yl)piperidin-4-yl]-N-methylcyclopropanesulfonamide
  • 1-[(2-Phenyl-1,3-thiazol-4-yl)methyl]-4-(1,3-thiazol-2-yloxy)piperidine
  • N-{1-[(3-bromophenyl)methyl]piperidin-3-yl}-N-methylcyclopropanesulfonamide
  • Tert-butyl 2-amino-2-(4-tert-butylphenyl)acetate
  • N-{1-[(2-bromophenyl)methyl]piperidin-3-yl}-N-methylcyclopropanesulfonamide
  • 4-[2-(4-{Pyrido[2,3-d]pyrimidin-4-yl}piperazin-1-yl)pyrimidin-4-yl]morpholine
  • 4-[6-(4-{Pyrido[2,3-d]pyrimidin-4-yl}piperazin-1-yl)pyridazin-3-yl]morpholine