Adenosine-2'-monophosphate

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Names

[ CAS No. ]:
130-49-4

[ Name ]:
Adenosine-2'-monophosphate

[Synonym ]:
Adenosine Monophosphate Hydrate (2'- and 3'- mixture) from Yeast
MFCD00151215
Adenosine 2'-monophosphate
Adenylic Acid Hydrate (2'- and 3'- mixture) from Yeast
Methionyl adenylate
adenosine 2'-monophosphoric acid
Adenosine 2'(3')-monophosphate mixed isomers
Adenosine 2'-phosphate
2'(3')-AMP Hydrate (2'- and 3'- mixture) from Yeast
Methioninyl adenylate
2'-Adenylic acid
EINECS 204-990-7
L-METHIONYL ADENYLATE
2'-adenosine monophosphate

Chemical & Physical Properties

[ Density]:
2.3±0.1 g/cm3

[ Boiling Point ]:
815.5±75.0 °C at 760 mmHg

[ Molecular Formula ]:
C10H14N5O7P

[ Molecular Weight ]:
347.221

[ Flash Point ]:
447.0±37.1 °C

[ Exact Mass ]:
347.063080

[ PSA ]:
195.88000

[ LogP ]:
-1.74

[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C

[ Index of Refraction ]:
1.905

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AU7480300
CHEMICAL NAME :
2'-Adenylic acid
CAS REGISTRY NUMBER :
130-49-4
BEILSTEIN REFERENCE NO. :
0058366
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H14-N5-O7-P

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 60,251,1954

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AU7480300

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Adenosine 2',3'-cyclic phosphate
  • Adenosine, adenylyl-(3'®5')-
  • (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(dichlorophosphoryloxymethyl)oxolane-3,4-diol
  • adenylyl-(2'-5')-adenylyl-(2'-5')-2',3'-O-(1-methoxyhexadecylidene)adenosine
  • [5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-[5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy-phosphinic acid
  • Adenosine
  • [5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-[5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy-phosphinic acid
  • Adenosine,5'-O-(triphenylmethyl)-

DownStream

  • Adenosine
  • beta-D-Ribofuranose (9CI)
  • 3'-Adenylic acid
  • 6H-Purin-6-imine, 1,7-dihydro- (9CI)
  • Adenine
  • D-ribo-3,4,5-Trihydroxy-2-phosphonooxy-valeraldehyd
  • D-ribo-2,4,5-Trihydroxy-3-phosphonooxy-valeraldehyd
  • Uridine, adenylyl-(3'®5')-

Articles

The RimL transacetylase provides resistance to translation inhibitor microcin C.

J. Bacteriol. 196(19) , 3377-85, (2014)

Peptide-nucleotide antibiotic microcin C (McC) is produced by some Escherichia coli strains. Inside a sensitive cell, McC is processed, releasing a nonhydrolyzable analog of aspartyl-adenylate, which ...

Aprataxin resolves adenylated RNA-DNA junctions to maintain genome integrity.

Nature 506(7486) , 111-5, (2014)

Faithful maintenance and propagation of eukaryotic genomes is ensured by three-step DNA ligation reactions used by ATP-dependent DNA ligases. Paradoxically, when DNA ligases encounter nicked DNA struc...

Eukaryotic elongation factor 2 kinase regulates the cold stress response by slowing translation elongation.

Biochem. J. 465(2) , 227-38, (2015)

Cells respond to external stress conditions by controlling gene expression, a process which occurs rapidly via post-transcriptional regulation at the level of protein synthesis. Global control of tran...


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Related Compounds

  • Adenosine-2'-monophosphate
  • adenosine-2'-monophosphate disodium salt
  • monomethyl adenosine 2'-monophosphate
  • monoisopropyl adenosine 2'-monophosphate
  • Adenosine 2',3'-cyclic phosphate
  • Adenosine, 2'-amino-2'-deoxy-, cyclic 3',5'-(hydrogen phosphate)
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2,2,9-Triethyl-1-oxa-5,9-diazaspiro[5.5]undecane
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • Methyl 1-(4-ethyl-1-hydroxycyclohexyl)-2-methylcyclopropane-1-carboxylate
  • tert-Butyl-DL-alanine