Eplivanserin hemifumarate

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Names

[ Name ]:
Eplivanserin hemifumarate

[Synonym ]:
Eplivanserin hemifumarate
(Z,E)-1-(2-Fluorophenyl)-3-(4-hydroxyphenyl)-2-propen-1-one O-[2-(dimethylamino)ethyl]oxime fumarate (2:1)
TRANS-2'-FLUORO-4-HYDROXYCHALCONE O-[(Z)-2-(DIMETHYLAMINO)ETHYL]OXIME--FUMARIC ACID (2:1)
SR-46349 hemifumarate salt

Chemical & Physical Properties

[ Boiling Point ]:
456.3ºC at 760mmHg

[ Molecular Formula ]:
C₂₃H₂₅FN₂O₆

[ Molecular Weight ]:
444.45300

[ Flash Point ]:
229.8ºC

[ Exact Mass ]:
444.17000

[ PSA ]:
119.66000

[ LogP ]:
3.23880

[ Vapour Pressure ]:
1.63E-08mmHg at 25°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H410

[ Precautionary Statements ]:
P273-P501

[ RIDADR ]:
UN 3077 9 / PGIII

Articles

Nest building is impaired in the Ts65Dn mouse model of Down syndrome and rescued by blocking 5HT2a receptors.

Neurobiol. Learn. Mem. 116 , 162-71, (2014)

Down syndrome (DS) has an incidence of about 1/700 births, and is therefore the most common cause of cognitive and behavioral impairments in children. Recent studies on mouse models of DS indicate tha...

Role of serotonin (5-HT)2 receptors in cocaine self-administration and seeking behavior in rats.

Pharmacol. Rep. 57(1) , 35-46, (2005)

Previous studies have indicated a role of serotonin (5-HT)2 receptors in modulation of the behavioral effects of cocaine. In the present study, the efficacy of SR 46349B (a 5-HT(2A) receptor antagonis...

Activation of slowly conducting medullary raphe-spinal neurons, including serotonergic neurons, increases cutaneous sympathetic vasomotor discharge in rabbit.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 288(4) , R909-18, (2005)

Neurons in the rostral medullary raphe/parapyramidal region regulate cutaneous sympathetic nerve discharge. Using focal electrical stimulation at different dorsoventral raphe/parapyramidal sites in an...

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