Dimethyl 2-oxopentanedioate

Suppliers

Names

[ Name ]:
Dimethyl 2-oxopentanedioate

[Synonym ]:
MFCD00048052
2-Ketoglutaric Acid Dimethyl Ester
Dimethyl 2-Ketoglutarate
Dimethyl 2-oxopentanedioate
Glutaric acid, 2-oxo-, dimethyl ester
Pentanedioic acid, 2-oxo-, dimethyl ester
2-Oxoglutaric Acid Dimethyl Ester
DiMethyl 2-Oxoglutarate
Dimethyl2-oxoglutarate

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
249.4±23.0 °C at 760 mmHg

[ Molecular Formula ]:
C₇H₁₀O₅

[ Molecular Weight ]:
174.151

[ Flash Point ]:
105.0±22.7 °C

[ Exact Mass ]:
174.052826

[ PSA ]:
69.67000

[ LogP ]:
-0.22

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.427

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918300090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Methanol
2-Ketoglutaric acid
diazomethane
N-(1-Methoxy-5,5-dimethyl-3-oxo-1-cyclohexen-1-yl)benzamid
METHYL 2,5-DIHYDRO-2,5-DIMETHOXY-2-FURANCARBOXYLATE
2-(Trimethylsiloxy)-2-pentenedioic acid dimethyl ester
N-(1-Methoxy-5,5-dimethyl-3-oxocyclohex-1-yl)benzamid
Methyl 2-furoate
Hydrochloric acid

DownStream

(S)-methyl 5-oxotetrahydrofuran-2-carboxylate
(R)-methyl 5-oxotetrahydrofuran-2-carboxylate
(2R)-2-hydroxyglutaric acid dimethyl ester
6-Bromoquinoline-2,4-dicarboxylic acid
pyrroloquinoline quinone
2,4-Quinolinedicarboxylicacid
methyl 2,3,5,6,11,11b-hexahydro-3-oxo-1H-indolizino[8,7-b]indole-11b-carboxylate
1,2,5,6,11,11b-Hexahydro-3H-indolizino[8,7-b]indol-3-one
Dimethyl 3-bromo-2-oxopentanedioate

Customs

[ HS Code ]: 2918300090

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

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PLoS ONE 9(12) , e115144, (2014)

Recent work has highlighted glutaminase (GLS) as a key player in cancer cell metabolism, providing glutamine-derived carbon and nitrogen to pathways that support proliferation. There is significant in...

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dimethyl 2-acetamido-3-oxopentanedioate
dimethyl 2-(ethoxymethylidene)-3-oxopentanedioate
dimethyl 2-(((benzyloxy)carbonyl)amino)-4-oxopentanedioate
dimethyl 2-hydroxy-2-methyl-4-oxopentanedioate
DIMETHYL 2-[2-(4-METHYLPHENYL)HYDRAZONO]-3-OXOPENTANEDIOATE
DIMETHYL 2-[2-(4-METHOXYPHENYL)HYDRAZONO]-3-OXOPENTANEDIOATE
2-(3-fluorobenzyl)-8-(piperidin-1-ylsulfonyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
2-(4-fluorobenzyl)-8-(piperidin-1-ylsulfonyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
2-(3,5-difluorobenzyl)-8-(piperidin-1-ylsulfonyl)[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
2-(2-chlorobenzyl)-8-(piperidin-1-ylsulfonyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
2-(4-chlorobenzyl)-8-(piperidin-1-ylsulfonyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
2-(3-bromobenzyl)-8-(piperidin-1-ylsulfonyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
8-((3,4-dihydroisoquinolin-2(1H)-yl)sulfonyl)-2-(3-fluorobenzyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
8-(azepan-1-ylsulfonyl)-2-(2,5-dimethylbenzyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
8-(azepane-1-sulfonyl)-2-[(3,5-difluorophenyl)methyl]-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-3-one
8-(azepan-1-ylsulfonyl)-2-(4-chlorobenzyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

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