Tryptanthrine

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Names

[ CAS No. ]:
13220-57-0

[ Name ]:
Tryptanthrine

[Synonym ]:
Tryptanthrin
MFCD00012073
indolo[2,1-b]quinazoline-6,12-dione

Chemical & Physical Properties

[ Density]:
1.45g/cm3

[ Boiling Point ]:
469.3ºC at 760 mmHg

[ Molecular Formula ]:
C₁₅H₈N₂O₂

[ Molecular Weight ]:
248.23600

[ Flash Point ]:
237.7ºC

[ Exact Mass ]:
248.05900

[ PSA ]:
51.96000

[ LogP ]:
1.93010

[ Vapour Pressure ]:
5.55E-09mmHg at 25°C

[ Index of Refraction ]:
1.762

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Tryptanthrin ameliorates atopic dermatitis through down-regulation of TSLP.

Arch. Biochem. Biophys. 542 , 14-20, (2014)

Atopic dermatitis (AD) is a common skin disease that greatly worsens quality of life. Thymic stromal lymphopoietin (TSLP) plays a decisive role in the development of AD. The purpose of this study is t...

Indigo naturalis and its component tryptanthrin exert anti-angiogenic effect by arresting cell cycle and inhibiting Akt and FAK signaling in human vascular endothelial cells.

J. Ethnopharmacol. 174 , 474-81, (2015)

Indigo naturalis has been used to treat inflammatory diseases and dermatosis, including psoriasis, since thousands of years in China. It has been proven effective in our previous clinical studies on t...

Kourokhitin, a potential drug containing two active substances.

Dokl. Biochem. Biophys. 426 , 131-3, (2009)

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