L-Aspartic acid β-(7-amido-4-methylcoumarin)
Suppliers
Names
[ CAS No. ]:
133628-73-6
[ Name ]:
L-Aspartic acid β-(7-amido-4-methylcoumarin)
[Synonym ]:
h-asp(amc)-oh
Chemical & Physical Properties
[ Density]:
1.452g/cm3
[ Boiling Point ]:
610ºC at 760mmHg
[ Molecular Formula ]:
C14H14N2O5
[ Molecular Weight ]:
290.27100
[ Flash Point ]:
322.7ºC
[ Exact Mass ]:
290.09000
[ PSA ]:
122.63000
[ LogP ]:
1.61520
[ Vapour Pressure ]:
9.8E-16mmHg at 25°C
[ Index of Refraction ]:
1.651
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Safety Phrases ]:
S22
[ RIDADR ]:
NONH for all modes of transport
Articles
J. Inherit. Metab. Dis. 16 , 929-934, (1993)
L-Aspartic acid-beta-7-amido-4-methylcoumarin is a sensitive and specific fluorogenic substrate for lysosomal glycoasparaginase (aspartylglucosaminidase). Fibroblasts and leukocytes from 8 patients wi...
Biochem. Biophys. Res. Commun. 377 , 1168-1172, (2008)
To elucidate the basis of aspartylglucosaminuria (AGU) from the viewpoint of enzyme structure, we constructed structural models of mutant aspartylglucosaminidase (AGA) proteins using molecular modelin...
Clin. Chem. 40 , 385-388, (1994)
Serum, plasma, and lymphocytes from aspartylglycosaminuria (AGU) patients and carriers and from normal controls were incubated with a fluorescent glycosylasparaginase substrate, L-aspartic acid beta-(...