INCB8761(PF-4136309)

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Names

[ CAS No. ]:
1341224-83-6

[ Name ]:
INCB8761(PF-4136309)

[Synonym ]:
incb8761
PF-4136309

Chemical & Physical Properties

[ Molecular Formula ]:
C29H31F3N6O3

[ Molecular Weight ]:
568.59000

[ Exact Mass ]:
568.24100

[ PSA ]:
120.34000

[ LogP ]:
4.02780

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-hydroxy-4-(5-(pyrimidin-2-yl)pyridine-2-yl) cyclohexanone
  • Benzamide, N-[2-[(3S)-3-amino-1-pyrrolidinyl]-2-oxoethyl]-3-(trifluoromethyl)-, hydrochloride (1:1)
  • 2,5-Dibromopyridine
  • 1,4-Dioxaspiro[4.5]decan-8-one
  • 8-(5-bromopyridin-2-yl)-1,4-dioxaspiro[4.5]decan-8-ol
  • 2-[3-(Trifluoromethyl)benzoyl]aminoacetic acid

DownStream

Related Compounds

  • INCB 8761
  • N-(2-((S)-3-(((1r,4S)-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide
  • GNF-Pf-2778
  • (R)-PF-06256142
  • GNF-PF-3777
  • N-Pf-homoserine tert-butyl ester
  • 3-chloro-2-(4-methoxy-1H-pyrazol-1-yl)benzaldehyde
  • 5-(2-ethyl-4-methyl-1H-imidazol-1-yl)pyridine-3-carbaldehyde
  • 4-[2-(Methylsulfanyl)ethyl]thiane-4-carbaldehyde
  • 1-[(Pyridazin-3-yl)methyl]cyclopropane-1-carbaldehyde
  • 4-(1-Methoxypropan-2-yl)thiane-4-carbaldehyde
  • 2-Methyl-2-[(pyrazin-2-yl)methyl]butanal
  • 1-(1-Ethoxyethyl)cyclobutane-1-carbaldehyde
  • 3-Ethyl-1-(2-methylpropyl)cyclopentane-1-carbaldehyde
  • 2,2-Dimethyl-3-(4-methyloxan-4-yl)propanal
  • 1-[1-(4-Bromophenyl)cyclopropyl]cyclopropane-1-carbaldehyde
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