INCB8761(PF-4136309)

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Names

[ CAS No. ]:
1341224-83-6

[ Name ]:
INCB8761(PF-4136309)

[Synonym ]:
incb8761
PF-4136309

Chemical & Physical Properties

[ Molecular Formula ]:
C29H31F3N6O3

[ Molecular Weight ]:
568.59000

[ Exact Mass ]:
568.24100

[ PSA ]:
120.34000

[ LogP ]:
4.02780

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-hydroxy-4-(5-(pyrimidin-2-yl)pyridine-2-yl) cyclohexanone
  • Benzamide, N-[2-[(3S)-3-amino-1-pyrrolidinyl]-2-oxoethyl]-3-(trifluoromethyl)-, hydrochloride (1:1)
  • 2,5-Dibromopyridine
  • 1,4-Dioxaspiro[4.5]decan-8-one
  • 8-(5-bromopyridin-2-yl)-1,4-dioxaspiro[4.5]decan-8-ol
  • 2-[3-(Trifluoromethyl)benzoyl]aminoacetic acid

DownStream

Related Compounds

  • INCB 8761
  • N-(2-((S)-3-(((1r,4S)-4-hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide
  • GNF-Pf-2778
  • (R)-PF-06256142
  • GNF-PF-3777
  • N-Pf-homoserine tert-butyl ester
  • 2,2,2-trichloroethyl 3-tert-butyl-1-(1-oxo-1,2,3,4-tetrahydroisoquinolin-7-yl)-1H-pyrazol-5-ylcarbamate
  • (4-Bromo-3,5-diethoxyphenyl)methanol
  • Methyl 2-(bromomethyl)-6-iodo-4-nitrobenzoate
  • N-[7-(1-Piperidinyl)-6-quinolinyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
  • 1H-pyrrole-2,5-dicarboxylic acid 2-ethyl ester 5-methyl ester
  • 1-Pyrrolidinecarboxamide, 3-(dimethylamino)-, (3R)-
  • 4-((Tert-butyldimethylsilyloxy) methyl)-2-methoxyaniline
  • 3-methoxy-4-nitro-N-phenylbenzamide
  • 4-amino-2-chloro-5-methoxy-N-phenyl-benzamide
  • tert-butyl 2-oxo-1-((1-tosyl-1H-indol-4-yl)methyl)-1,9-diazaspiro[5.5]undecane-9-carboxylate
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