ACTINONIN

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Names

[ CAS No. ]:
13434-13-4

[ Name ]:
ACTINONIN

[Synonym ]:
Butanediamide, N-hydroxy-N-[(1S)-1-[[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]carbonyl]-2-methylpropyl]-2-pentyl-, (2R)-
Actinonine
MFCD00080257
hylpropyl)carbamoyl)
(2R)-N-Hydroxy-N-{(2S)-1-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl}-2-pentylsuccinamide
(2R)-N-Hydroxy-N-{(2S)-1-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-3-methyl-1-oxo-2-butanyl}-2-pentylsuccinamide

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Melting Point ]:
137-139ºC

[ Molecular Formula ]:
C19H35N3O5

[ Molecular Weight ]:
385.498

[ Exact Mass ]:
385.257660

[ PSA ]:
118.97000

[ LogP ]:
0.59

[ Index of Refraction ]:
1.513

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RG9900700
CHEMICAL NAME :
Octanohydroxamic acid, 3-((1-((2-(hydroxymethyl)-1-pyrrolidinyl)carbonyl)-2- methylpropyl) carbamoyl)-
CAS REGISTRY NUMBER :
13434-13-4
LAST UPDATED :
199512
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C19-H35-N3-O5
MOLECULAR WEIGHT :
385.57
WISWESSER LINE NOTATION :
T5NTJ AVYY1&1&MVY5&1VMQ B1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 38,1629,1985
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85FZAT "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds., Tokyo, Univ. of Tokyo Press, 1967 Volume(issue)/page/year: -,102,1967
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #167936

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
RG9900700

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Related Compounds

  • actinonin
  • O-O-Dibenzyl-(-)-actinonin
  • Polanrazine A
  • benzyl N-[2-(4-bromophenyl)-2-methylpropyl]carbamate
  • benzyl N-{1-[(4-bromophenyl)methyl]cyclopropyl}carbamate
  • Tert-butyl 3-(trifluoroacetyl)azetidine-1-carboxylate
  • (R)-(2,2-dimethyl-1,3-dioxolan-4-yl)diphenylmethanol
  • 1-tert-Butyl 2-cyclopentyl (2S)-piperazine-1,2-dicarboxylate
  • butyl 6-bromo-2-(tetrahydropyran-4-ylamino)pyrimidine-4-carboxylate
  • (3S)-3-amino-3-(2-fluoro-4-methylphenyl)propanoic acid
  • 2-(4-(But-2-ynoyl)piperazin-1-yl)-4-(3-(phenylcarbamoyl)phenyl)thiazole-5-carboxamide
  • 5-amino-3-(4-phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazole-4-carbonitrile
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