Methyl N-methylglycinate hydrochloride

Suppliers

Names

[ Name ]:
Methyl N-methylglycinate hydrochloride

[Synonym ]:
Methyl N-methylglycinate hydrochloride (1:1)
Methyl 2-(methylamino)acetate hydrochloride
H-Sar-OMe·HCl
methyl 2-(methylamino)acetate,hydrochloride
Glycine, N-methyl-, methyl ester, hydrochloride
EINECS 236-853-2
Glycine, N-methyl-, methyl ester, hydrochloride (1:1)
Sarcosine Methyl Ester Hydrochloride
MFCD00038876
Sarcosine methyl ester,hydrochloride
H-Sar-OMe.HCl
Methyl N-methylglycinate hydrochloride

Chemical & Physical Properties

[ Density]:
0.964g/cm3

[ Boiling Point ]:
118.9ºC at 760 mmHg

[ Melting Point ]:
117-119 °C(lit.)

[ Molecular Formula ]:
C₄H₁₀ClNO₂

[ Molecular Weight ]:
139.581

[ Flash Point ]:
25.7ºC

[ Exact Mass ]:
139.040009

[ PSA ]:
38.33000

[ LogP ]:
0.57170

[ Vapour Pressure ]:
16.3mmHg at 25°C

[ Index of Refraction ]:
1.4

[ Storage condition ]:
Store at RT.

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R37/38;R41

[ Safety Phrases ]:
S26-S39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

N-Boc-N-methylglycine methyl ester
Methanol
Sarcosine
methyl iodide
2-(methylamino)acetyl chloride

DownStream

1H-Pyrrole-2-carboxylicacid, 1-methyl-, methyl ester
N-Boc-N-methylglycine methyl ester
N,N'-DIMETHYLTHIOHYDANTOIN
N-ACRYLOYLSARCOSINE METHYL ESTER
4-METHYL-3,4-DIHYDRO-1H-BENZO[E][1,4]DIAZEPINE-2,5-DIONE
Methyl 1-methylimidazole-5-carboxylate
1-Methyl-1H-imidazole-5-carboxamide
2-(Methylamino)acetohydrazide
Z-Gly-Sar-OH
2H-Imidazole-2-thione, 1, 3-dihydro-1,3-dimethyl-

Customs

[ HS Code ]: 2923900090

[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Role of transglutaminase in insulin release. Study with glycine and sarcosine methylesters.

Endocrinology 117(1) , 237-42, (1985)

The Ca2+-responsive enzyme transglutaminase, which catalyzes the cross-bridging of proteins, is present in pancreatic islet cells, but its participation in the process of insulin release remains to be...

Inhibition of the formation of myotubes in vitro by inhibitors of transglutaminase.

Biochim. Biophys. Acta 762(3) , 429-36, (1983)

The effects of competitive inhibitors of transglutaminase on the formation of myotubes by the fusion of myoblasts in vitro has been investigated. Myotube formation was inhibited when myoblasts from 11...

Poly(N-acryloylsarcosine methyl ester) protein-resistant surfaces.

J. Phys. Chem. B 109(44) , 20923-8, (2005)

A new class of protein-resistant film based on N-substituted glycine derivatives is described. Pulsed plasma deposited poly(N-acryloylsarcosine methyl ester) coatings are shown to be resistant toward ...

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