Methyl N-methylglycinate hydrochloride

Methyl N-methylglycinate hydrochloride Structure
Methyl N-methylglycinate hydrochloride structure
Common Name Methyl N-methylglycinate hydrochloride
CAS Number 13515-93-0 Molecular Weight 139.581
Density 0.964g/cm3 Boiling Point 118.9ºC at 760 mmHg
Molecular Formula C4H10ClNO2 Melting Point 117-119 °C(lit.)
MSDS Chinese USA Flash Point 25.7ºC
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

Role of transglutaminase in insulin release. Study with glycine and sarcosine methylesters.

Endocrinology 117(1) , 237-42, (1985)

The Ca2+-responsive enzyme transglutaminase, which catalyzes the cross-bridging of proteins, is present in pancreatic islet cells, but its participation in the process of insulin release remains to be documented. Glycine methylester (1.0-10.0 mM) inhibited, i...

Inhibition of the formation of myotubes in vitro by inhibitors of transglutaminase.

Biochim. Biophys. Acta 762(3) , 429-36, (1983)

The effects of competitive inhibitors of transglutaminase on the formation of myotubes by the fusion of myoblasts in vitro has been investigated. Myotube formation was inhibited when myoblasts from 11-day-old chick embryos were cultured in vitro in the presen...

Poly(N-acryloylsarcosine methyl ester) protein-resistant surfaces.

J. Phys. Chem. B 109(44) , 20923-8, (2005)

A new class of protein-resistant film based on N-substituted glycine derivatives is described. Pulsed plasma deposited poly(N-acryloylsarcosine methyl ester) coatings are shown to be resistant toward the adsorption of fibrinogen and lysozyme. Deposition and U...

Transglutaminase and cellular motile events: retardation of proinsulin conversion by glycine methylester.

Biosci. Rep. 5(7) , 581-7, (1985)

Glycine methyl ester, an inhibitor of transglutaminase, decreased glucose-stimulated insulin release and delayed proinsulin conversion in rat pancreatic islets pulse-labelled with L-[4-3H]phenylalanine. Sarcosine methyl ester, which does not inhibit transglut...

Transglutaminase involvement in the secretion of insulin from electropermeabilised rat islets of Langerhans.

Biosci. Rep. 10(6) , 557-61, (1990)

Ca(2+)-Induced insulin release from electropermeabilised islets is inhibited by the transglutaminase inhibitors monodansylcadaverine, glycine methylester, methylamine and cystamine but not by the control compounds dimethyl monodansylcadaverine and sarcosine m...