Foropafant

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Names

[ CAS No. ]:
136468-36-5

[ Name ]:
Foropafant

[Synonym ]:
MFCD00904759

Chemical & Physical Properties

[ Density]:
1.065g/cm3

[ Boiling Point ]:
571.6ºC at 760mmHg

[ Molecular Formula ]:
C28H40N4S

[ Molecular Weight ]:
464.70900

[ Flash Point ]:
299.5ºC

[ Exact Mass ]:
464.29700

[ PSA ]:
60.50000

[ LogP ]:
7.14350

[ Vapour Pressure ]:
4.49E-13mmHg at 25°C

[ Index of Refraction ]:
1.575

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Articles

Platelet-activating factor (PAF) is not an essential component of the cascade leading to smooth muscle cell proliferation following vascular injury.

J. Lipid Mediat. Cell Signal. 12(1) , 49-57, (1995)

In order to evaluate the relative importance platelet-activating factor (PAF) in the proliferative process leading to restenosis, the effect of SR 27417, a novel highly potent PAF receptor antagonist,...

Prevention of platelet-activating factor-induced gastrointestinal lesions in rats by the new specific antagonist N-(2-dimethylaminoethyl)-N-(3-pyridinylmethyl)[4-(2,4,6-triisopropylphe nyl) thiazol-2yl]amine.

Arzneimittelforschung 46(4) , 407-12, (1996)

SR 27417 (CAS 136468-36-5, N-(2-dimethylaminoethyl)-N-(3-pyridinylmethyl)[4-(2,4,6-triisop ropylphenyl) thiazol-2-yl]amine), a highly potent platelet-activating factor (PAF) receptor antagonist, was t...

Role of platelet activating factor in the intestinal epithelial secretory and Chinese hamster ovary cell cytoskeletal responses to cholera toxin.

Proc. Natl. Acad. Sci. U. S. A. 91(20) , 9655-8, (1994)

With the recent heightened concern about cholera around the world come new questions about the mechanism by which cholera toxin causes diarrhea. Peterson and Ochoa have suggested that prostaglandin sy...


More Articles

Related Compounds

  • 4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-[(3S)-3-methylmorpholin-4-yl]-5-oxopentanoic acid
  • 2-{N-benzyl-1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-fluorophenyl]formamido}acetic acid
  • 4-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanamido]-2-methylbut-2-enoic acid
  • 4-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylbutanamido]-2-methylbut-2-enoic acid
  • (3R)-1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylbut-2-enoyl]piperidine-3-carboxylic acid
  • 2-{1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylbut-2-enamido]cyclobutyl}acetic acid
  • 1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylbut-2-enoyl]-3-methylpyrrolidine-3-carboxylic acid
  • 2-[(1RS,2SR)-2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanamido]cyclopentyl]acetic acid
  • rac-2-[(1R,2S)-2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2,2-difluoropropanamido]cyclopentyl]acetic acid
  • 5-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetamido}-3-methylpentanoic acid
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