4-(bromomethyl)phenyl acetic acid
Suppliers
Names
[ CAS No. ]:
13737-36-5
[ Name ]:
4-(bromomethyl)phenyl acetic acid
[Synonym ]:
4-(Carboxymethyl)benzyl Bromide
2-[4-(bromomethyl)phenyl]acetic acid
MFCD00010632
4-(BROMOMETHYL)PHENYLACETIC ACID
Benzeneacetic acid, 4-(bromomethyl)-
[4-(Bromomethyl)phenyl]acetic acid
4-(bromomethyl)phenyl acetic acid
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Boiling Point ]:
343.1±22.0 °C at 760 mmHg
[ Melting Point ]:
179-183 °C(lit.)
[ Molecular Formula ]:
C9H9BrO2
[ Molecular Weight ]:
229.071
[ Flash Point ]:
161.3±22.3 °C
[ Exact Mass ]:
227.978592
[ PSA ]:
37.30000
[ LogP ]:
2.21
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.599
[ Storage condition ]:
Store at RT.
MSDS
Safety Information
[ Symbol ]:
GHS07, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H315-H319-H334-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338-P342 + P311
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36/37/38;R42
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
UN3261
[ WGK Germany ]:
3
[ Packaging Group ]:
III
[ Hazard Class ]:
8
[ HS Code ]:
2916399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2916399090
[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
J. Chem. Soc. Chem. Commun. , 399, (1993)
J. Med. Chem. 35 , 4297, (1992)
Previously, we have reported that some guanidino-substituted alpha- and beta-aryl enol lactones I and II behaved as selective, mechanism-based inhibitors of some trypsin-like proteases (Rai, R.; Katze...
Bioorg. Med. Chem. Lett. 19(8) , 2270-2, (2009)
We have developed a novel and moderately selective COX-2 inhibitor, imrecoxib, as a new anti-inflammatory drug. We describe herein the preparation of the major metabolites M2 and M4 of imrecoxib, as w...