4-(bromomethyl)phenyl acetic acid
4-(bromomethyl)phenyl acetic acid structure
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Common Name | 4-(bromomethyl)phenyl acetic acid | ||
|---|---|---|---|---|
| CAS Number | 13737-36-5 | Molecular Weight | 229.071 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 343.1±22.0 °C at 760 mmHg | |
| Molecular Formula | C9H9BrO2 | Melting Point | 179-183 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 161.3±22.3 °C | |
| Symbol |
GHS07, GHS08 |
Signal Word | Danger | |
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J. Chem. Soc. Chem. Commun. , 399, (1993)
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Effect of conformational mobility and hydrogen-bonding interactions on the selectivity of some guanidinoaryl-substituted mechanism-based inhibitors of trypsin-like serine proteases.
J. Med. Chem. 35 , 4297, (1992) Previously, we have reported that some guanidino-substituted alpha- and beta-aryl enol lactones I and II behaved as selective, mechanism-based inhibitors of some trypsin-like proteases (Rai, R.; Katzenellenbogen, J.A. J. Med. Chem., submitted). In this study,... |
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Synthesis and anti-inflammatory activity of the major metabolites of imrecoxib.
Bioorg. Med. Chem. Lett. 19(8) , 2270-2, (2009) We have developed a novel and moderately selective COX-2 inhibitor, imrecoxib, as a new anti-inflammatory drug. We describe herein the preparation of the major metabolites M2 and M4 of imrecoxib, as well as the in vitro and in vivo activities of the two compo... |